Palladium-catalyzed coupling of heteroaromatic triflates with acetylene and its application for a dynemicin A intermediate

Article abstract of DOI:10.1016/0040-4020(95)00118-R

An acetylene moiety was introduced to a carbonyl carbon of amide group via its triflate in the presence of palladium catalyst. The reaction proceeded smoothly under mild conditions. Utilizing this methodology, a model compound of dynemicin A bearing acety