Bioorganic and Medicinal Chemistry Letters p. 2887 - 2892 (1997)
Update date:2022-08-28
Topics:
Shankaran
Donnelly, Karla L.
Shah, Shrenik K.
Humes, John L.
Pacholok, Stephen G.
Grant, Stephan K.
Green, Barbara G.
MacCoss, Malcolm
A series of benzoxazolones has been synthesized using modifications of literature methods. The synthetic benzoxazolone analogs, along with commercially available analogs, were evaluated as inhibitors of nitric oxide synthases (NOS). Structure-activity relationships are also discussed.
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