Chemistry of Heterocyclic Compounds p. 167 - 170 (1999)
Update date:2022-08-16
Topics:
Kovalenko
Sytnik
Nikitchenko
Rusanova
Chernykh
Porokhnyak
A new method for the synthesis of 3-(1,3,4-oxadiazol-2-yl)coumarins is proposed. It is based on the recyclization of 2-(N-aroylhydrazono)coumarin-3-carboxamides, which are readily obtained by the reaction of 2-iminocoumarin-3-carboxamides with arenecarboxylic hydrazides in an acidic medium. Advantages of the given method over alternative synthetic schemes were shown. Proposals on the mechanism of reaction were made. 1999 KluwerAcademic/Plenum.
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