3'-C-hydroxymethylthymidine: Synthesis and incorporation into oligodeoxynucleotide analogues

Article abstract of DOI:10.1080/15257779508012502

The stereoselective synthesis of 3'-C-hydroxymethylthymidine (5) in five steps from thymidine has been accomplished and this nucleoside has been incorporated into oligodeoxynucleotides (ODNs) in different ways.

Full text of DOI:10.1080/15257779508012502

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3′-C-Hydroxymethylthymidine:
Synthesis and Incorporation into
Oligodeoxynucleotide Analogues
Pia N⊘ncgaard J⊘rgensen a , Margit L. Svendsen a , Claus Nielsen b
& Jesper Wengel a
a Department of Chemistry , Odense University , DK-5230, Odense M,
Denmark
b Retrovirus Laboratory, Department of Virology, States
Seruminstitut. Artillerivej , 5, DK-2300, Copenhagen, Denmark
Published online: 16 Feb 2007.
To cite this article: Pia N⊘ncgaard J⊘rgensen , Margit L. Svendsen , Claus Nielsen & Jesper Wengel
(1995) 3′-C-Hydroxymethylthymidine: Synthesis and Incorporation into Oligodeoxynucleotide
Analogues, Nucleosides and Nucleotides, 14:3-5, 921-924
To link to this article: http://dx.doi.org/10.1080/15257779508012502
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