2-Alkyl-substituted histamines and hydroxyethylimidazoles with G-protein-stimulatory activity

DOI: 10.1016/0223-5234(96)89166-5

Source and publish data:

European Journal of Medicinal Chemistry p. 397 - 405 (1996)

Update date:2022-07-29

Topics:

Authors:

Detert Detert

Leschke Leschke

Toegel Toegel

Seifert Seifert

Schunack

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Article abstract of DOI:10.1016/0223-5234(96)89166-5

Cationic-amphiphilic 2-substituted histamines activate pertussis toxin-sensitive guanine nucleotide-binding proteins (G-proteins) by a receptor-independent mechanism. From our recent studies it became apparent that lipophilicity is an important determinan

Full text of DOI:10.1016/0223-5234(96)89166-5

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