INFLUENCE OF ENOLATE GEOMETRY AND STRUCTURE ON THE STEREOCHEMISTRY OF THE ASYMMETRIC OXIDATION OF PROCHIRAL KETONE ENOLATES TO OPTICALLY ACTIVE α-HYDROXY KETONES

Article abstract of DOI:10.1016/S0040-4039(01)80611-0

The stereoselectivity for the asymmetric oxidation of enolates to optically active α-hydroxy ketones using (+)-(camphorylsulphonyl)oxaziridine is dependent on the enolate substitution pattern, the solution structure of the enolate and to a lesser extent the enolate geometry.