Solid phase synthesis of oligonucleotide phosphorothioate analogues using bis(ethoxythiocarbonyl)tetrasulfide as a new sulfur-transfer reagent

DOI: 10.1016/S0040-4039(98)00307-4

Source and publish data:

Tetrahedron Letters p. 2467 - 2470 (1998)

Update date:2022-08-10

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Authors:

Zhang, Zhaoda

Nichols, Alexandra

Alsbeti, Mazen

Tang, Jimmy X.

Tang, Jin Yan

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Article abstract of DOI:10.1016/S0040-4039(98)00307-4

A new sulfur-transfer reagent, bis(ethoxythiocarbonyl)tetrasulfide (1), has been prepared and used for the synthesis of oligonucleotide phosphorothioates via solid phase phosphoramidite approach.

Full text of DOI:10.1016/S0040-4039(98)00307-4

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