A chiral bimetallic Lewis acid as a reaction template. Asymmetric reduction of unsymmetric ketones with LiBH4

Article abstract of DOI:10.1246/bcsj.72.1109

A new series of chiral bimetallic Lewis acids, 5,5'-bis[(R)-2-aryl- 1,3,2-dioxaborolan-4-one], have been prepared from L-(+)-tartaric acid and arylboronic acids. In the presence of these Lewis acids, unsymmetric ketones were reduced quantitatively by LiBH