Synthesis and antibacterial activity of 4″ or 6″-alkanoylamino derivatives of arbekacin

DOI: 10.1038/ja.2015.61

Source and publish data:

Journal of Antibiotics p. 741 - 747 (2015)

Update date:2022-08-17

Topics:

Authors:

Sasaki, Kazushige

Kobayashi, Yoshihiko

Kurihara, Takashi

Yamashita, Yohei

Takahashi, Yoshiaki

Miyake, Toshiaki

Akamatsu, Yuzuru

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Article abstract of DOI:10.1038/ja.2015.61

Arbekacin, an aminoglycoside antibiotic, is an important drug because it shows a potent efficacy against methicillin-resistant Staphylococcus aureus. However, resistance to arbekacin, which is caused mainly by the bifunctional aminoglycoside-modifying enz

Full text of DOI:10.1038/ja.2015.61

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Product name:3,2',6',3'',4'''-pentakis(N-tert-butoxucarbonyl)arbekacin

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