Tetrahedron Letters p. 1801 - 1804 (1983)
Update date:2022-08-11
Topics:
Yamaguchi, Ryohei
Nakazono, Yutaka
Kawanisi, Mituyosi
Whereas alkyl Grignard reagents undergo 1,2- and 1,4-additions to N-methoxycarbonyl-pyridinium chloride in a variable ratio, alkenyl and alkynyl Grignard reagents do the exclusive 1,2-addition to afford 2-substituted N-methoxycarbonyl-1,2-dihydropyridines in fair to excellent yields.
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Doi:10.1021/jo00223a056
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(1970)
