Tetrahedron p. 4121 - 4126 (1983)
Update date:2022-08-30
Topics:
Yde, B.
Thomsen, I.
Thorsen, M.
Clausen,K.
Lawesson, S.-O.
The protected aspartame, 4, has been prepared from the benzyl ester of N-benzyloxycarbonyl-S-aspartic acid, 1, and the methyl S-phenylalanate, 3, using 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide, LR, as a coupling reagent.Another protected aspartame, 7, has been prepared from the tert-butyl ester of 1-
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