INSECT PHEROMONES AND THEIR ANALOGS. XV. THE SYNTHESIS OF 9-OXODEC-2E-ENOIC ACID - A PHEROMONE OF THE HONEYBEE Apis melliferana

Article abstract of DOI:10.1007/BF00599271

A new effective route to the synthesis of 7-oxooctanal has been found which is based on the ozonolysis of the tetrahydropyran-2-yl ether of 7-methyloct-7-en-1-ol - the product of the coupling of the readily available methallyl chloride and the Grignard reagent from the corresponding ether of 5-bromopentan-1-ol.From the 7-oxooctanal has been obtained 9-oxodec-2E-enoic acid - a pheromone of the honeybee Apis melliferana.