Helvetica Chimica Acta p. 1039 - 1045 (1983)
Update date:2022-08-11
Topics:
Riggio, Gaetano
Hopff, Wolfgang Herbert
Hofmann, Alfred Andre
Waser, Peter Gaudenz
It was our aim to reactivate acetylcholinesterase poisoned with sarin.We synthesized 2-(o-hydroxyphenyl)-1-methylpyridinium-iodide (9), 2-(p-hydroxyphenyl)-1-methylpyridinium-iodide (19) and 4-(o-hydroxyphenyl)-1-methylpyridinium-iodide (14) as potential reactivators.All substances showed moderate toxicity against mice; their reactivity potency in vitro and in vivo was negligible.
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Doi:10.1134/S1070427208060311
(2008)Doi:10.1016/S0040-4039(03)01199-7
(2003)Doi:10.1021/ol016651x
(2001)Doi:10.1021/ja01544a081
(1958)Doi:10.1016/j.bmcl.2014.11.087
(2015)Doi:10.1142/S1088424613500612
(2013)
