A new C2-symmetric chiral bisphosphine ligand containing a bioxazole backbone: Highly enantioselective hydrosilylation of ketones

Article abstract of DOI:10.1016/S0957-4166(97)00554-5

C₂-Symmetric (4S,4'S)-2,2'-bis(o-diphenylphosphinophenyl-4,4',5,5'-tetrahydro-4,4'-bi(1,3 -oxazole) (1, Phos-Biox) has been designed and synthesized as a chiral ligand for metal-catalyzed reactions. The Phos-Biox 1 was found to be an efficient