Hemiaminals of trifluoroacetaldehyde, as trifluoromethylating agents

DOI: 10.1016/S0040-4039(99)01369-6

Source and publish data:

Tetrahedron Letters p. 6411 - 6414 (1999)

Update date:2022-08-11

Topics:

Authors:

Mispelaere, Clotilde

Roques, Nicolas

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(99)01369-6

Hemiaminals of trifluoroacetaldehyde are new trifluoromethylating agents. These reagents are synthesised from amines and gaseous trifluoroacetaldehyde. tBuONa is able to deprotonate the hemiaminals to form trifluoromethyl anion equivalents CF₃CH(O^-)NMe₂. The trifluoromethyl anion has been transferred from such intermediates to benzaldehyde yielding phenyl (trifluoromethyl) methanol.

Full text of DOI:10.1016/S0040-4039(99)01369-6

Products guided by the article

Product name:1-PHENYL-2,2,2-TRIFLUOROETHANOL

Cas No:340-04-5

R&D Labs maybe for 340-04-5

Qingzhou Baibang import and export co.,Ltd

Contact:+86-536-3265899

Address:No.338, Tuoshan Road
Tianjin Ji Ping Jia Chemical Co., Ltd.

Contact:18622448868

Address:tianjin
Xiamen Huasing Chemicals Co.Ltd.

Contact:0086-592-6228397

Address:NO.24, Xinglin North 2nd Road,Jimei district
HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.

Contact:+86-186-02659358

Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China
Shandong Yubin Chemical CO.,LTD

website:http://www.yukaichem.com/en.html

Contact:+86-536-8865336

Address:binhai economic development zone，262737 shangdong，china

Relevant to this article

Autooxidation of Δ¹⁷⁽²⁰⁾-20-hydroxy derivatives of steroids. Synthesis of 3β-acetoxy-17α-hydroperoxy-16α- methylpregn-5-en-20-one and its reduction to 17α-hydroxy derivative

Doi:10.1134/S1070428011010052
(2011)
Palladium-catalysed direct arylation of heteroarenes using 1-(bromophenyl)-1,2,3-triazoles as aryl source

Doi:10.1016/j.catcom.2016.12.030
(2017)
Photocycloadditions of 4-Methoxy-2-pyridone to Olefins and Synthesis of 1,2-Dihydrocyclobutapyridin-3(4H)-ones

Doi:10.1039/c39800000537
(1980)
Pathways in Chromic Acid Oxidations. 3. Kinetics and Mechanism of Oxidation of Malonic acid

Doi:10.1021/jo00219a051
(1985)
Acyclic Tetraethynylethene Molecular Scaffolding: Multinanometer-Sized Linearly Conjugated Rods with the Poly(triacetylene) Backbone and Cross-Conjugated Expanded Dendralenes

Doi:10.1002/hlca.19950780402
(1995)
Photooxidations of 2-(γ,ε-dihydroxyalkyl) furans in water: Synthesis of DE-bicycles of the pectenotoxins

Doi:10.1021/ol3007937
(2012)

Article Doi