A new synthesis of pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-diones by oxidative N-N bond formation of 6-amino-5-(N-aryliminomethyl)uracils using iodobenzene diacetate

Article abstract of DOI:10.1055/s-1997-1073

The intramolecular cyclizations of 6-amino-5-(N-aryliminomethyl)-1,3-dimethyluracils (2) involving the N-N bond formation were effected via a hypervalent iodine oxidation using iodobenzene diacetate. This method enabled a facile synthesis of 2-aryl-5,7-di