Beitrag zur Analytik und Synthese von 3-Hydroxy-4-oxocarotinoiden

Article abstract of DOI:10.1002/hlca.19800630635

(3RS,3'RS)-Astaxanthin (=3,3'-dihydroxy-β,β-carotene-4,4'-dione, 1:1-mixture of racemate and meso-form; 1) can be separated into its optical isomers (3S,3'S)-1a, (3R,3'R)-1b and meso-(3R,3'S)-1c via the corresponding diastereomeric di-(-)-camphanates.Some aspects of the configurational stability of astaxanthin are discussed. - HPLC. analysis of the (-)-camphanates of 3-hydroxy-4-oxocarotenoids provides, in suitable cases and supported by spectroscopic data, an analytical method for the simultaneous determination of constitution and chiralty.