Bioorganic and Medicinal Chemistry Letters p. 139 - 142 (1998)
Update date:2022-08-11
Topics:
Armer, Richard E.
Dutton, Christopher J.
Fenner, Brian R.
Greenwood, Sean D. W.
Hall, Kim T.
Rudge, Andrew J.
Carbocyclic analogues of the antibacterial natural product frenolicin B have been synthesised. These analogues were active against parasitic protozoa of the genus Eimeria and represent a new series of anticoccidial agents. The synthesis of simplified analogues helped to define a possible pharmacophore for frenolicin.
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