Synthesis of 2-[Mercapto(cyano)methylene]-1,2,3,4-tetrahydroquinazolin-4-ones and 2-Amino-4-methylpyrazolo-[1,5-a]quinazolin-5(4H)-one

Article abstract of DOI:10.1002/jhet.5570340426

A series of 2-[mercapto(cyano)methylene]-1,2,3,4-tetrahydroquinazolin-4-ones and 2-amino-4-methylpyrazolo[1,5-a]quinazolin-5(4H)-one were prepared from 2-cyanomethylquinazolin-4(3H)-ones via α-bromo derivatives 4 and amide oxime 8, respectively. The new compounds have been characterized by elemental analyses and ¹H-nmr, in some cases by ir and ¹³C-nmr investigations.