
Journal of the Chemical Society. Chemical communications p. 82 - 83 (1981)
Update date:2022-08-16
Topics:
Ucciani, Eugene
Bonfand, Andre
Under hydroformylation conditions, using supported rhodium as catalyst, 2-nitrostyrene is directly converted into skatole in ca. 70percent yield, by a reaction involving formation of 2-(o-nitrophenyl)propionaldehyde by homogeneous catalysis, reduction of the nitro-group by heterogeneous catalysis, then ring closure and thermal dehydration.
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