Journal of Pharmaceutical Sciences p. 639 - 642 (1975)
Update date:2022-08-11
Topics:
Kornet
Thio
Malone
Lubawy
A series of 3 amino 3 methyloxindoles was synthesized from indoles by modification of previously described procedures. All compounds showed activity against chloroform induced arrhythmias in mice. One member of the series, 3 methyl 3 piperidinooxindole, displayed activity equal to that of lidocaine while showing only one third the acute toxicity.
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Doi:10.1021/jo00318a010
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