Synthetic analogs of Peganum alkaloids VIII. A quantum-mechanical investigation of the reduction of deoxypeganine and its derivatives

Article abstract of DOI:10.1007/BF02234934

The alkaloid deoxypeganine and some of its derivatives have been subjected to reduction with sodium tetrahydroborate and with the complex NaBH₄·BF₃·Et₂O. It has been shown that the structures of the reduction products depend on the presence and positions of substituent s in the benzene ring. The quantum-chemical calculations performed have confirmed the probable formation of reduced structures of the type of o-aminobenzylpyrrolidine and the type of a macrocyclic diamine.