An Efficient Synthesis of the Plant Growth Hormone 1-Triacontanol

Article abstract of DOI:10.1007/BF00807430

A high yield synthesis of 1-triacontanol was based on the cheap and easily available starting materials 1-octadecanol and 1,12-dodecanediol.The first one was converted to octadecanal using a phase transfer system, whereas the second one after phase transfer bromination and reaction with triphenylphosphine provided 1-hydroxy-12-triphenylphosphonium bromide.Wittig reaction of these two synthons and subsequent hydrogenation furnished the desired product. - Keywords: 1-Triacontanol: Wittig reaction; Phase transfer reaction; Plant growth hormone