Studies on metabolites of mycoparasitic fungi. III. New sesquiterpene alcohol from Trichoderma koningii

Article abstract of DOI:10.1248/cpb.43.1035

A new sesquiterpene alcohol, named tricho-acorenol (1), was isolated from the culture broth of Trichoderma koningii OUDEMANS along with methyl benzoate (2), cyclonerodiol (3), cyclo-(L-Pro-L-Leu) (4), 4-hydroxyphenethyl alcohol (5), uracil (7), and a ceramide (6). The ceramide (6) was identified as (2S,3S,4R)-2-[(2R)-2-hydroxytetracosanoylamino]-1,3,4-octadecanetriol by the use of ion-spray ionization MS (ISI-MS) and comparison of the optical rotation and the ¹H-NMR data with those of (2S,3S,4R)-2-[(2R)-2-hydroxytetracosanoylamino]-1,3,4-hexadecanetriol. The structure of tricho-acorenol was elucidated to be (1S,4S,5S,7R)-1-isopropyl-4,8-dimethyl-spiro-[4.5]dec-8-en-7-ol on the basis of chemical and spectroscopic evidence.

Full text of DOI:10.1248/cpb.43.1035

NII-Electronic Library Service

NII-Electronic Library Service

NII-Electronic Library Service

NII-Electronic Library Service