Bioorganic and Medicinal Chemistry Letters p. 2141 - 2144 (1999)
Update date:2022-08-30
Topics:
Mikata, Yuji
Kishigami, Maki
Nishida, Mamiko
Yano, Shigenobu
Kawamoto, Tetsuji
Ikeuchi, Yoshihiro
Yoneda, Fumio
Electrolytically reduced 6- and 8-nitro-5-deazaflavin derivatives have been found to interact to react specifically with guanine base by means of cyclic voltammetry. Electrolytic reductions of 6- and 8-nitro-5-deazaflavin derivatives in the presence of the 2'-deoxyguanosine under anaerobic conditions resulted in prominent formation of 8-oxo-7,8-dihydro-2'- deoxyguanosine.
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