Electrochemically Generated Copper Carbonyl for Selective Dimethyl Carbonate Synthesis

Article abstract of DOI:10.1021/acscatal.8b03682

Development of electrochemical synthesis routes for high-value chemicals could pave the way for a sustainable chemical industry based on electricity. Herein, the electrochemical synthesis of the industrially relevant and environmentally benign reagent, dimethyl carbonate (DMC), is investigated. By utilizing a combination of electrochemical techniques, in situ infrared spectroscopy, and headspace-gas chromatography-mass spectrometry we show production and spectroelectrochemical evidence for the synthesis of DMC via an electrochemically generated copper carbonyl species. The formation of the copper carbonyl has close to 100% current efficiency, in the applied potential range of 0.1-0.4 V vs SCE. Subsequent formation of DMC occurs with a slow reaction time on the order of 30-40 days. Relative to potential coproducts, the reaction is highly selective for DMC. Optimization of the reaction may lead to a viable method of DMC production.

Full text of DOI:10.1021/acscatal.8b03682

Subscriber access provided by University of South Dakota
Article
Electrochemically generated copper carbonyl
for selective dimethyl carbonate synthesis
Bethan Jane Venceslau Davies, Manuel Šari#, Marta C Figueiredo, Niels C Schjødt, Søren
Dahl, Poul Georg Moses, Maria Escudero-Escribano, Matthias Arenz, and Jan Rossmeisl
ACS Catal., Just Accepted Manuscript • DOI: 10.1021/acscatal.8b03682 • Publication Date (Web): 14 Dec 2018
Downloaded from http://pubs.acs.org on December 14, 2018
Just Accepted
“Just Accepted” manuscripts have been peer-reviewed and accepted for publication. They are posted
online prior to technical editing, formatting for publication and author proofing. The American Chemical
Society provides “Just Accepted” as a service to the research community to expedite the dissemination
of scientific material as soon as possible after acceptance. “Just Accepted” manuscripts appear in
full in PDF format accompanied by an HTML abstract. “Just Accepted” manuscripts have been fully
peer reviewed, but should not be considered the official version of record. They are citable by the
Digital Object Identifier (DOI®). “Just Accepted” is an optional service offered to authors. Therefore,
the “Just Accepted” Web site may not include all articles that will be published in the journal. After
a manuscript is technically edited and formatted, it will be removed from the “Just Accepted” Web
site and published as an ASAP article. Note that technical editing may introduce minor changes
to the manuscript text and/or graphics which could affect content, and all legal disclaimers and
ethical guidelines that apply to the journal pertain. ACS cannot be held responsible for errors or
consequences arising from the use of information contained in these “Just Accepted” manuscripts.
is published by the American Chemical Society. 1155 Sixteenth Street N.W.,
Washington, DC 20036
Published by American Chemical Society. Copyright © American Chemical Society.
However, no copyright claim is made to original U.S. Government works, or works
produced by employees of any Commonwealth realm Crown government in the
course of their duties.

Page 1 of 26
ACS Catalysis
1
2
3
4
5
6
7
8
9
Electrochemically generated copper carbonyl
for selective dimethyl carbonate synthesis
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
Bethan J. V. Davies1, Manuel Šarić1, 2, Marta C. Figueiredo1†, Niels C. Schjødt3, Søren Dahl3,
Poul Georg Moses3, María Escudero-Escribano1*, Matthias Arenz1, 4*, Jan Rossmeisl1*
1Nano-Science Center, Department of Chemistry, University of Copenhagen,
Universitetsparken 5, 2100 Copenhagen, Denmark. 2Center for Atomic Scale Materials
Design (CAMd), Department of Physics, Technical University of Denmark, Fysikvej
building 307, 2800 Kongens Lyngby, Denmark. 3Haldor Topsøe A/S, Nymøllevej 55, 2800
Kongens Lyngby, Denmark. 4Department of Chemistry and Biochemistry, University of
Bern, Freiestrasse 3, 3012 Bern, Switzerland
KEYWORDS copper, dimethyl carbonate, electrosynthesis, spectroelectrochemistry,
methanol
ABSTRACT
Development of electrochemical synthesis routes for high-value chemicals could pave the way
for a sustainable chemical industry based on electricity. Herein, the electrochemical synthesis
of the industrially relevant and environmentally benign reagent, dimethyl carbonate is
investigated. By utilizing a combination of electrochemical techniques, in situ infrared
spectroscopy and headspace-gas chromatography-mass spectrometry we show production and
spectroelectrochemical evidence for the synthesis of DMC via an electrochemically generated
copper carbonyl species. The formation of the copper carbonyl has close to 100% current
efficiency, in the applied potential range of 0.1 – 0.4 V vs SCE. Subsequent formation of DMC
1
ACS Paragon Plus Environment

ACS Catalysis
Page 2 of 26
1
2
3
4
5
6
7
8
9
occurs with a slow reaction time on the order of 30-40 days. Relative to potential co-products,
the reaction is highly selective for DMC. Optimization of the reaction may lead to a viable
method of DMC production.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
INTRODUCTION.
Organic electrosynthesis has the potential to replace current environmentally harmful synthesis
methods of the chemical industry1–3. Electrosynthesis uses inherently clean electrons as the
redox reagent, rather than aggressive chemicals. Electrosynthesis also generally generates less
waste from spent reagents than stoichiometric or catalytic processes. Traditional chemical
synthesis methods rely on fossil fuels as the energy source, whereas the energy input to drive
the electrochemical reaction can be sourced from renewables, such as wind or solar.
Dimethyl carbonate (DMC) is a versatile chemical; it is environmentally benign and an
industrially relevant chemical reagent and solvent4. Moreover, DMC is a value-added product
of methanol and has potential to replace toxic phosgene and methyl halides for carbonylation
and methylation, respectively. Replacement with DMC would transform such processes into
Green Chemistry synthesis reactions5–9. DMC is also used as an electrolyte component in
lithium ion batteries10. Since the demand for energy storage by the use of batteries is
increasing11, the production of DMC is likely to concomitantly increase12.
The current industrial methods for producing DMC are energy intensive and hazardous,
requiring high temperature and pressure to drive the reaction13,14. They also use dangerous
combinations of reactants (CO and O2 or NOx)2,3. From a Green Chemistry perspective, these
conditions and reactant combinations should be avoided and there has been increasing
investigation into alternative and electrochemical methods for DMC synthesis15.
Electrochemical synthesis of DMC uses the electrochemical potential as the driving force,
rather than high temperature and high pressure16,17. The synthesis reactions of DMC performed
2
ACS Paragon Plus Environment

Page 3 of 26
ACS Catalysis
1
2
3
4
5
6
by electrochemical and chemical oxidation methods are shown in Equation 1 and Equation 2
respectively18.
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
Equation 1
2CH3OH + CO→(CH3O)2CO + 2H + +2e ―
Equation 2
1
2
2CH3OH + CO + O2→(CH3O)2CO + H2O
Possible co-products of the reaction are dimethyl oxalate (DMO), dimethyl ether (DME),
dimethoxymethane (DMM), and methyl formate (MF)16,19–22. Direct oxidation of methanol to
CO2 as a competing reaction is also often observed16,19–22. The by-product for the chemical
synthesis (Equation 2Equation 1) is water, which is waste and requires treatment. The by-
products for the electrochemical synthesis on the other hand are “clean” protons and electrons2
(Equation 1Equation 2Equation 2). These by-products could be used to make hydrogen, a
valuable fuel. Reducing the amount of waste products is a step towards a more environmentally
friendly chemical industry.
Electrosynthesis of DMC has been performed by a variety of techniques and with a wide
range of materials. Metallic gold and palladium have both been shown to be active for
electrocatalytic synthesis of DMC16,19,20,22–24 and the surface reactions of these metals have
been well studied by in-situ spectroscopy24. Various metal compounds have also shown to be
21,25
promising as electrode materials, such as PdCl2 and CuCl2
as well as indirect
,
electrochemical systems based on solution phase redox mediators such as the Br2/Br-
system20,26. However, as far as the authors are aware, there has been no commercial application
of electrochemical synthesis of DMC as of yet.
3
ACS Paragon Plus Environment

ACS Catalysis
Page 4 of 26
1
2
3
4
5
6
7
8
9
Herein, we continue the search for alternative and electrochemical methods of DMC
synthesis by using a combination of theory and experiment. Guided by theoretical calculations
on potentially suitable electrode materials, experimental investigations are performed on
copper electrodes.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
RESULTS AND DISCUSSION.
Thermodynamic analysis.
To investigate suitable electrode materials for electrocatalytic synthesis of DMC,
thermodynamic analysis of the reaction was performed using density functional theory (DFT).
Electrocatalytic synthesis of DMC requires adsorption of the reactants to the electrode surface.
Adsorption energies of methoxy and carbon monoxide were selected as descriptors for the
synthesis reaction of DMC on an electrode surface. The analysis focused on the energy
efficiency of the reaction so that a better catalyst, in energy terms, than Au and Pd could be
found. Energy efficiency is indicated by the ability to run the synthesis at a low potential. The
applied potential is used for activation of methanol by the electrode to methoxy (CH3O*), which
leads to production of DMC (Equation 3) (* indicates a surface adsorbed species or vacant
surface site). From the DFT analysis it is concluded that the potential (in V vs RHE) which
needs to be applied to activate methanol corresponds to the adsorption energy of methoxy (in
eV). Details of the DFT calculations can be found in the Supplementary Information.
Equation 3
2CH3O ∗ + CO ∗ ↔ CH3OCOOCH3 + 3 ∗
A good catalyst candidate should bind methoxy strongly to lower the overpotential for
methanol oxidation and bind CO to obtain a coverage of CO*. However, the catalyst should on
the other hand bind CO* and methoxy weak enough that the intermediates to not block the
surface and reaction 3 is fast. A promising metal balancing both requirements is Cu (adsorption
4
ACS Paragon Plus Environment

Page 5 of 26
ACS Catalysis
1
2
3
4
5
6
7
8
9
energy of methanol is 0.3 eV) as it activates methanol at a potential much lower than both Au
(1.3 eV) and Pd (0.8 eV). This lower required potential indicates that copper should be more
energy efficient than both Au and Pd. Following this analysis, copper was chosen as an
electrode material to be investigated experimentally for electrochemical DMC synthesis.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
Electrochemical activity.
The electrochemical activity of an electrode can be investigated by use of cyclic voltammetry.
In cyclic voltammetry, a set potential range is scanned from one end to the other and back with
a defined scan rate. Oxidation and reduction reactions can be observed by changes in the current
response, by positive and negative signals respectively. In Figure 1 the cyclic voltammograms
(CV) for a copper wire electrode recorded in an argon-saturated and CO-saturated electrolyte
solution of 0.1 M NaClO4 in methanol are presented. The potential range was scanned between
-0.8 and 0.8 V vs. SCE at a rate of 100 mV/s. In the CV recorded with an argon-saturated
electrolyte, peaks are observed for both oxidation and reduction reactions labelled as Ox1, Ox2
and Red1, Red2 respectively. The oxidation peaks are due to the formation of various copper
oxides and hydroxides in the form of Cu(I), Cu(II), whereas the reduction peaks can be assigned
to the reduction of these oxide species to form Cu(I) and Cu(0)27,28. Additionally, oxidation of
the solvent, methanol, likely occurs from Ox1 onwards as well as copper dissolution. The
reaction peaks indicate a degree of reversibility for some of the oxidation processes recorded,
however, as the oxidation peak area is visibly larger than the reduction peak area, irreversible
reactions are likely occurring, such as the oxidation of the solvent. The CV is comparable to
that recorded in a similar electrolyte solution, where a broad oxidation peak is shown in the
forward scan and a smaller reduction peak observed in the reverse scan29.
On the addition of carbon monoxide (CO) gas to the electrolyte solution, a large
oxidation peak Ox3 appears (Figure 1). The onset of this peak is before the onset of copper
5
ACS Paragon Plus Environment

ACS Catalysis
Page 6 of 26
1
2
3
4
5
6
7
8
9
oxidation observed without CO present in the argon saturated electrolyte solution. This peak
covers the range of copper oxides/hydroxides formation. The continued presence of the two
reduction peaks Red1 and Red2, indicates that the oxidation of copper still occurs and is
unaffected by the new CO induced oxidation reaction. There is no corresponding reduction
peak for the oxidation peak Ox3, indicating that it is an irreversible reaction. The Ox3 reaction
is highly active in the methanol electrolyte solution and a comparable response is not observed
for an aqueous electrolyte solution on the addition of CO (see Supplementary Information for
CVs in 0.1 M NaClO4(aq)).
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
The CO initiated oxidation process shows passivation from about 0.4 V on the
forward scan and hysteresis between the two scan directions. This is suggestive of a surface
deactivation at post peak potentials on the forward scan which is reactivated on the reverse
scan at a lower potential. This is not an uncommon observation for the oxidation of alcohols or
small organic molecules over metal surfaces. Oxidation products can cover the surface,
passivating it towards further reactions. On the reverse scan, the products desorb or get reduced,
so that the surface becomes available for reaction again30.
Figure 1. Cyclic voltammograms recorded with a wire copper electrode in an argon (black)
and carbon monoxide (blue) saturated electrolyte solution of 0.1 M NaClO4 in methanol. The
potentials were scanned at a rate of 100 mV/s, in the directions indicated by the arrows. The
6
ACS Paragon Plus Environment

Page 7 of 26
ACS Catalysis
1
2
3
4
5
6
counter electrode was copper mesh and the reference potential was a saturated calomel
electrode (SCE). Geometrical current densities are presented.
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
Spectroelectrochemistry.
Spectroelectrochemistry was performed using Fourier-transform infrared spectroscopy (FTIR)
coupled with electrochemistry. An electrode of polycrystalline copper was used to study
surface reactions, including formation of intermediates and products. Spectra were
recorded at different electrode potentials in the electrochemically active range of copper
in a CO environment (0.0 to 0.5 V vs. SCE), as determined to be the potential range of
interest from the CV in Figure 1. Figure 2 shows the FTIR spectra in both argon-saturated
(A) and CO-saturated (B) electrolyte solutions.
In an argon-saturated atmosphere (Figure 2A) five main bands are observed, at 2341,
-
2053, 2025-2019, 1372 and 1145 cm-1. The positive band at 1145 cm-1 is due to ClO4 ions
from the supporting electrolyte. As the electrode potential is made more positive, the
-
negatively charged ClO4 ions concentrate in the vicinity of the electrode and
consequently, the thin layer, leading to the observed increase in the band intensity. The
band at 2053 cm-1 can be assigned to an overtone from methanol24. The fact that it appears
as a negative feature at potentials higher than 0.2 V vs. SCE suggests that methanol
decomposition starts in this potential range. In fact, concomitant with this negative band,
two positive bands are observed in the spectra at 2025-2019 and 1372 cm-1 corresponding
-
to (adsorbed) CO and HCO3 , respectively. Both CO and bicarbonate (CO2) can be
suggested as products from methanol direct oxidation oxidation31 and are observed at
potentials higher than 0.2 V vs. SCE.
7
ACS Paragon Plus Environment

ACS Catalysis
Page 8 of 26
1
2
3
4
5
6
7
8
9
The CO related band around 2020 cm-1 is potential dependent as expected from adsorbed
CO species and shifts 20 cm-1 V-1. This band has been reported in the literature, for
aqueous solutions and negative applied potentials (bellow the potential of zero charge) as
CO adsorbed on metallic copper atoms32,33
.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
The band at 2341 cm-1 is due to O-C-O stretching from CO2. Unfortunately, as our
specular compartment is not under vacuum, fluctuation of the CO2 and water vapor content
in the chamber can exist and affect the intensity of this band (positive or negative), making
the interpretation of the potential formation of this possible product difficult. However,
when CO2 is dissolved in liquid a single band is observed instead of a double band. In
Figure 2B the single band is therefore indicative of CO2 in solution produced from
methanol oxidation. The double band observed in Figure 2A is attributed to gas phase CO2
in the specular compartment which may be obscuring a single positive band. Additionally,
the presence of the bicarbonate band indicates that CO2 is formed from methanol oxidation
at the Cu electrode when the applied potential is higher than 0.2 V vs. SCE in both Figure
2A and B.
When the spectroelectrochemical cell is saturated with CO, the spectra (Figure 2B)
change. The most prominent difference is the observation of a positive vibrational feature
at 2106 cm-1 and a negative one at 1646 cm-1. The latter is due to water oxidation in the
thin layer, while the former band at 2106 cm-1 should be related with a CO species as it
falls in the vibrational region where carbonyl bands are expected. In fact, such a band has
been ascribed in literature to the formation of a Cu(I)CO complex in solution29,34,35
.
Furthermore, the band does not change with the applied potential, suggesting that it is
indeed related with a solution species.
8
ACS Paragon Plus Environment

Page 9 of 26
ACS Catalysis
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
Figure 2. Infrared spectroelectrochemistry. Thin-film spectra for a copper electrode in (A)
argon and (B) CO saturated electrolyte solutions of 0.1 M NaClO4/methanol. Spectra were
acquired from -0.2 in steps of 0.1 up to 0.5 V vs SCE, at 100 interferograms per spectrum and
8 cm-1 resolution. The backgrounds were recorded at -0.2 VSCE in the respective saturated
solution.
In Figure 3, the integrated band area of the peak at 2106 cm-1 as a function of electrode
potential is presented. Integration of the Cu(I)CO band area provides a qualitative measure of
the quantity of the species present at a given potential. The Cu(I)CO band can be observed in
the spectra at potentials as low as 0 V vs. SCE, increasing in intensity up to 0.2 V vs. SCE and
then decreasing. Most likely, copper dissolution is initiated at 0 V vs. SCE forming Cu(I) in
solution, that in the presence of CO produces a cuprous CuCO species. This electrochemical
activity correlates with the CO-induced oxidation peak Ox3, in the CV of Figure 1
9
ACS Paragon Plus Environment

ACS Catalysis
Page 10 of 26
1
2
3
4
5
6
7
8
9
From 0.3 V vs. SCE onwards, both Cu(I) oxidation to Cu(II) and CO oxidation to CO2 begin,
decreasing the amount of Cu(I)CO species in solution, as observed from the lower intensity of
the FTIR band at potentials higher than 0.3 V. When the electrode potential is higher than 0.2
V vs. SCE, bands similar to those observed in the absence of CO, are observed (band observed
at 2341 cm-1 and bicarbonate band at 1372 cm-1). These bands are probably due to methanol
and CO oxidation to CO2.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
There is no evidence of DMC formation on the surface of the copper electrode, as neither
vibrational features for DMC nor the methoxy surface intermedate are observed24,36
.
Figure 3. The [CuCO]+ 2106 cm-1 integrated carbonyl band area at each applied potential from
FTIR measurements provides a qualitative measure of the quantity of CuCO present at the
different potentials. The potentials were applied from low to high potential.
Constant-potential electrolysis.
Constant-potential electrolysis was used to investigate potential dependent synthesis reactions.
In these experiments, a selected potential was held for a set duration, after which, product
analysis was performed. The electrolysis potential is held long enough to generate appreciable
quantities of product for detection.
Based on the cyclic voltammograms of the copper electrode in Figure 1, a region of
electrochemical activity is observed between 0 and 0.4 VSCE for the CO/methanol system. In
10
ACS Paragon Plus Environment

Page 11 of 26
ACS Catalysis
1
2
3
4
5
6
7
8
9
addition to that, the recorded spectra in Figure 2 show that an interesting copper complex is
being formed in this same potential range. In order to investigate the activity of the copper
electrode and therewith, the CuCO species, for DMC synthesis, we performed electrolysis in
this potential region. We focused our subsequent investigation on selectivity towards DMC
production, Faradaic efficiency (FE) and potential dependence. The FE is determined by
quantifying the charge generated for the DMC reaction and relating that to the total charge
generated during the electrolysis.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
Figure 4A shows the generated current densities, normalized to the geometric surface
area (geo) of the electrode, for each electrolysis-potential. Good stability is obtained over the
course of the experiment, after an initial induction period of approximately 5 minutes. The
stabilized current densities were in the range of 0.1 to 4.5 mA cm-2geo. The trend in current
densities follows that of the CV, where the peak in current density is between 0.2 and 0.4 V. It
can also be seen that the CuCO band area (Figure 3) shows a similar trend as well, where the
current density is highest, the reaction rate of formation is highest and so is the band intensity.
Analysis of the electrolyte solution immediately after the experiment revealed that DMC had
not been produced, which is in agreement with the FTIR measurements (Figure 2). However,
the samples were monitored over the course of 70 days and shortly after the experiment (1-2
days), DMC was present in the solution and its concentration slowly increased with time. In
Figure 4B, the DMC concentration on day 3 and day 70 after the electrolysis is shown, where
less than 5µM was detected on day 3 for each potential and by day 70, up to 24 µM DMC was
detected. The DMC synthesis was initiated by the electrolysis and completed in solution until
a maximum DMC concentration was reached. The insert in Figure 4B shows that the reaction
starts to plateau at approximately day 40. The stability of the intermediate and slowness of the
synthesis reaction, may be related to the stabilizing effect of the CO ligand, which is known to
impart stability to copper perchlorate in solution37.
11
ACS Paragon Plus Environment

ACS Catalysis
Page 12 of 26
1
2
3
4
5
6
7
8
9
There is synthesis activity for DMC in the same applied potential range as seen for the CO-
induced CV oxidation peak and for CuCO formation, that is between 0 and 0.4 VSCE. The
highest concentrations were at 0.1 and 0.2 V. This potential-dependent and post-electrolysis
formation of DMC indicates that an indirect electrochemical synthesis is taking place, through
an electrochemically generated CuCO species. The reaction is selective for DMC as no other
possible products were detected, as defined earlier.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
Figure 4. Electrochemical synthesis. (A) constant potential electrolysis geometric current
densities for a copper disk electrode. Experiments were performed in CO saturated 0.1 M
NaClO4/methanol electrolyte solution each for 30 minutes, the counter electrode was copper
mesh and the reference potential was the SCE. (B) concentration of DMC at 3 and 70 days after
electrolysis. (B, insert) change of DMC concentration with time since the day of electrolysis,
shown for 0.1 V vs. SCE. Duplicate or triplicate measurements at all potentials were performed,
except 0.4 V vs. SCE and error bars show one standard deviation from the mean value.
Selectivity analysis.
The efficiency of charge passed, the Faraday efficiency (FE), for DMC formation is shown for
day 3 and day 70 after electrolysis Figure 5A. The FE is in the range of 1-6% for the applied
potentials tested. Therefore, even though there is a high selectivity for DMC, the majority of
the CuCO species formed is utilized for another reaction or is deactivated.
12
ACS Paragon Plus Environment

Page 13 of 26
ACS Catalysis
1
2
3
4
5
6
7
8
9
The electrochemically-generated CuCO species is observed in the same potential region
where DMC is formed, it is therefore hypothesized herein, that this Cu(I) species is the initiator
for DMC synthesis from CO and methanol. The selectivity observed for DMC versus other
possible products, indicates that the CuCO species is highly selective for DMC and Cu(I) is
indeed well known for having a high selectivity for DMC synthesis in heterogeneous
catalysis15.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
The production and FE of DMC is therefore directly related and limited to the FE of Cu(I),
since the Cu(I) species is the precursor to DMC. Additionally, the yield of DMC will be related
to, and limited by, the efficiency of the post-electrolysis homogeneous reaction. Therefore, the
degree of Cu(I) dissolution into the electrolyte solution may elucidate the efficiency of the
homogeneous reaction. Chemical analysis was performed on the electrolyte solutions to
investigate the copper content. In Figure 5, the Cu concentration in the electrolysis solutions
are presented. The concentration increases from 0.0 to 0.2 V vs. SCE and then stays relatively
constant up until 0.4 V vs. SCE. Due to the low current generated at 0.5 V vs. SCE the quantity
of copper in solution could not be determined as the signal was below the detection limit.
Relating the observed Cu concentrations from 0 to 0.4 V vs. SCE to the charge passed during
electrolysis shows close to 100% FE for the one electron oxidation reaction of Cu to Cu(I)
Figure 5, suggesting a significant loss of the bulk electrode. However, a proportion of the
current is likely to be due to the oxidation of Cu and Cu(I) to Cu(II), especially at more positive
potentials. The chemical analysis performed only provides the concentration of copper and not
the oxidation state. Therefore, the current density generated may be partly due to a combination
of different Cu oxidation reactions as well as solvent oxidation reactions which were indicated
by the spectroelectrochemistry results.
13
ACS Paragon Plus Environment

ACS Catalysis
Page 14 of 26
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
Figure 5. (A) Faraday efficiency (FE) for DMC and total charge passed during electrolysis at
each applied potential of 30 minutes. FE is shown for both 3 and 70 days after electrolysis.
(B) Concentration of copper in the electrolyte solution after electrolysis and resulting FE based
on one electron oxidation of Cu to Cu(I). Copper determination at 0.5 V vs. SCE was below
the detection limit and is therefore not shown. The resulting error in concentration of 1-2
replicate measurements at all potentials except 0.4 V vs. SCE are shown as one standard
deviation from the mean value. At 0.4 the error of calibration is presented.
As the FE is close to 100% for Cu(I) formation between 0.1 and 0.4 V vs. SCE and features
in the CV and spectroelectrochemical data show that the Cu(I) is formed from 0 up until 0.5 V,
we identify the Cu(I)CO as the electrochemically generated, active and selective, species for
DMC synthesis. Since the formation of Cu(I)CO appears to be highly efficient, it is likely that
it is the homogenous step that is the limiting factor for DMC formation. It is observed that the
CuCO reacts slowly, peaking around day 40 (Figure 4B insert) with a low FE. Oxidation of
methanol to methoxy must occur in order to form DMC with the CuCO+ intermediate.
Therefore, based on Equation 2, where molecular oxygen is the oxidant, a tentative
homogeneous reaction mechanism is presented by Equation 4, Equation 5 with the
electrochemical step shown by Equation 6.
14
ACS Paragon Plus Environment

Page 15 of 26
ACS Catalysis
1
2
3
4
5
6
7
8
Equation 4
Equation 5
[CuCO] + + 2CH3OH + ½O2→[Cu(OCH3)2CO] + + H2O
[Cu(OCH3)2CO] + → Cu + + (CH3O)2CO
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
Where the [CuCO]+ intermediate is generated electrochemically by:
Equation 6
(
)
Cu + COE 0.0 ― 0.4 V [CuCO] + + e ―
SCE
The homogeneous reactions occur in a sealed environment with CO and air. The CO
originating from saturation of the electrolyte solution during electrolysis and the air (i.e.
oxygen) from inevitable introduction during sample collection. The slow homogenous process
may then be due to poor kinetics, low oxygen exposure or a combination of the two. Additional
tests with increased oxygen exposure however, did not result in the immediate formation of
DMC, therefore, slow kinetics may be the underlying problem for this reaction and further
studies are required.
Due to the complexity of the electrochemical synthesis of DMC under these conditions,
the technique is not a viable one for production before significant optimization is performed.
However, these initial synthesis results also highlight the complexities and difficulties of
investigating electrochemical reactions. In the instance that a homogenous step is quick for
chemical formation, an indirect electrochemical synthesis may be mistaken for an
electrocatalytic synthesis. This will impact analysis and optimization strategies and may be
relevant for other investigations of electrocatalytic reactions, such as CO2 reduction38,39
.
15
ACS Paragon Plus Environment

ACS Catalysis
Page 16 of 26
1
2
3
4
5
6
CONCLUSIONS
7
8
9
The combination of the experimental techniques of FTIR, constant potential electrolysis and
HS-GS-MS has allowed us to study and understand the electrochemical synthesis of DMC on
copper in detail. Our results show that copper does not act as a direct electrocatalyst for
methanol carbonylation to DMC, rather, it acts as an indirect electrochemical catalyst. The
spectroelectrochemical measurements do not show adsorbed methoxy, a known intermediate
for direct electrochemical synthesis of DMC. The electrolysis tests, show that DMC is not
immediately formed during synthesis. Interestingly, DMC was subsequently formed in the
electrolyte solution. By using FTIR we observed a copper carbonyl (CuCO) formed by
oxidative dissolution of the electrode in a CO saturated electrolyte solution. Dissolution to
CuCO was found to be highly active and efficient with almost 100% FE and high and stable
current densities for its generation. Formation of CuCO occurred over a wide potential range,
from 0-0.5 V vs SCE. By using HS-GC-MS, we determined that DMC was formed in the
electrolyte in the same potential range as the CuCO species was formed. The resulting current
efficiency for DMC suffers from an inefficient chemical step and is on the order of 5% and is
therefore not yet a viable method of DMC production. However, as yet, no optimization of the
chemical step has been attempted. We concluded that the electrochemically generated CuCO
species is active and selective for DMC synthesis in solution, by an indirect electrochemical
mechanism.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
DFT analysis initiated our experimental investigation of copper as an electrocatalyst and lead
to the discovery of an indirect electrochemical synthesis route for DMC. The simulation is
limited in the absence of known competing reactions, such as that of copper dissolution to from
CuCO. We therefore emphasize the necessity of feed-back loops from theory and experiment
to further develop the predictive technique, as one approach advances the other.
16
ACS Paragon Plus Environment

Page 17 of 26
ACS Catalysis
1
2
3
4
5
6
7
EXPERIMENTAL SECTION
8
9
Chemicals.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
The electrolyte was NaClO4.H2O (VWR, AnalaR NORMAPUR, ≥99.0%) dissolved in
methanol (ultrapure, spectrophotometric grade 99.8ꢀ+ꢀ% Alfa Aesar) to form a 0.1 M
solution of NaClO4/methanol. This electrolyte was used for all electrochemical measurements.
Gasses used were argon (Air Liquide, Alphagaz 1.0, 99.999%) and carbon monoxide (Air
Liquide, >99.95). All chemicals were used as received from the supplier.
Electrochemical measurements.
The cyclic voltammetry and electrolysis tests were performed in a three electrode divided H-
cell connected to a potentiostat (Nordic EC ECi-200). The reference potential was a saturated
calomel electrode (SCE) and the counter electrode was copper mesh. The working electrode
for CV experiments consisted of a copper wire. The working electrode for electrolysis
measurements consisted of a copper disk of 6.35 mm diameter x 3 mm height placed in a Teflon
holder (Figure S3). The disk was flush with the end of the holder to produce a geometric surface
area of 0.32 cm2 which used to calculate the current density, J in mA cm-2geo. Before each
experiment, the electrode was polished until a smooth mirror like surface was visible by 1µM
then 0.3µM aluminum oxide suspension. The electrode was rinsed and solicited with ultrapure
water between polishes. Finally, the electrode was sonicated in methanol and left to dry before
electrochemical measurements were performed.
All compartments of the cell contained the same electrolyte solution with the working
electrode compartment containing a measured 20 mL. The solution in the working electrode
compartment was bubbled with either argon or carbon monoxide. To insure complete saturation
of the electrolyte solution during electrolysis, CO at atmospheric pressure was continuously
17
ACS Paragon Plus Environment

ACS Catalysis
Page 18 of 26
1
2
3
4
5
6
7
8
9
bubbled. Each electrolysis test was performed for 30 minutes, after which, the electrolyte
solution was collected for analysis in crimp sealed vials and were kept in these vials for
HSGCMS analysis. During the experiment there is an over pressure of CO which results in the
purging of air out of the cell, however, when the samples are collected, the lid of the H-cell
must be opened and the bubbling of CO stopped, therefore, air is also contained within the
vials. Between each electrolysis text, the cell was thoroughly rinsed with ultrapure water and
methanol, and then dried. All experiments were performed at room temperature. A diagram of
the cell used for electrochemical measurements can be found in the Supplementary
Information.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
Chemical analysis.
Quantitative chemical analysis was performed by an Agilent headspace sampler connected to
a gas chromatograph with a mass spectrometry detector (HS-GC-MS). Chemical separation
was achieved with an Agilent VF-624 column. The carrier gas was helium. The analysis
method allowed for the observation of dimethyl carbonate, dimethyl oxalate, methyl formate,
dimethoxy methane and dimethyl ether, tested by analyzing prepared reference solutions for
mass spectra and retention time matches.
Determination of the copper concentration was performed using an inductively coupled
plasma-mass spectrometer (ICP-MS). External calibration was performed with standards of
known concentration. Samples were diluted in 2%vol HNO3 prior to analysis. Further details on
calibration and analysis can be found in the Supplementary Information.
The Faradaic efficiency (FE) is calculated by,
eFni
FEi =
Q
18
ACS Paragon Plus Environment

Page 19 of 26
ACS Catalysis
1
2
3
4
5
6
7
8
9
where e is the number of electrons transferred per mole of product, F is the Faraday constant
in C mol-1, ni is the quantity of product i in mol and Q is the amount of charge passed during
the electrolysis in C.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
Spectroelectrochemistry.
For the spectroelectrochemistry measurements, a Thermo Fisher Nicolet 6700 spectrometer,
equipped with a specular reflectance unit (VeeMAX II, PIKE Technologies) and a MCT
detector was used. The experiments were performed in external reflection mode with a thin-
layer configuration, using a glass three electrode spectroelectrochemical cell as described
elsewhere40. The reference electrode potential as the SCE and counter electrode was platinum
foil. The copper electrode was pressed against a CaF2 prism at a controlled potential (-0.2 V
vs. SCE) where a reference spectrum was obtained. Then, the electrode potential was stepped,
successively to the sample potential where the sample spectra were recorded. The final spectra
are presented as (R-R0)/R0, where R and R0 is the reflectance at the sample and reference
potential, respectively. Therefore, for the results presented in this work mean that positive
bands in the spectra correspond to species with increased concentration and negative band to
species with lower concentration in the sample potential, compared to the reference. Each
spectrum corresponds to the collection of 100 scans with a resolution of 8 cm-1 which takes
approximately 1 minute to complete. All measurements were recorded at room temperature.
ASSOCIATED CONTENT
Supporting Information. The following file is available free of charge.
Chemical quantification and electrolysis cell setup design (PDF).
AUTHOR INFORMATION
Corresponding Authors
19
ACS Paragon Plus Environment

ACS Catalysis
Page 20 of 26
1
2
3
4
*E-mail:
5
6
7
8
9
maria.escudero@chem.ku.dk
matthias.arenz@dcb.unibe.ch
jan.rossmeisl@chem.ku.dk
Present Addresses
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
†Avantium, Zekeringstraat 29, 1014 BV, Amsterdamn, Netherlands
Notes
The authors declare no competing financial interest.
ACKNOWLEDGEMENTS
We acknowledge financial support from Innovation Fund Denmark (Grand Solutions
ProActivE 5124-00003ꢀA).
ABBREVIATIONS
CV, cyclic voltammetry; HSGCMS, headspace sampler gas chromatograph mass spectrometer;
FE, Faradaic efficiency.
REFERENCES
(1)
Sequeira, C. A. C.; Santos, D. M. F. Electrochemical Routes for Industrial Synthesis. J.
Braz. Chem. Soc. 2009, 20, 387–406.
(2)
Frontana-Uribe, B. A.; Little, R. D.; Ibanez, J. G.; Palma, A.; Vasquez-Medrano, R.
Organic Electrosynthesis: A Promising Green Methodology in Organic Chemistry.
Green Chem. 2010, 12, 2099.
20
ACS Paragon Plus Environment

Page 21 of 26
ACS Catalysis
1
2
3
4
5
6
7
8
9
(3)
Cardoso, D. S. P.; Šljukić, B.; Santos, D. M. F.; Sequeira, C. A. C. Organic
Electrosynthesis: From Laboratorial Practice to Industrial Applications. Org. Process
Res. Dev. 2017, 1213–1226.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
(4)
(5)
(6)
(7)
(8)
Aricò, F.; Tundo, P. Dimethyl Carbonate as a Modern Green Reagent and Solvent. Russ.
Chem. Rev. 2010, 79, 479–489.
Tundo, P.; Selva, M. The Chemistry of Dimethyl Carbonate. Acc. Chem. Res. 2002, 35,
706–716.
Ono, Y. Dimethyl Carbonate for Environmentally Benign Reactions. Pure Appl. Chem.
1996, 68, 367–375.
Ono, Y. Catalysis in the Production and Reactions of Dimethyl Carbonate, an
Environmentally Benign Building Block. Appl. Catal. A Gen. 1997, 155, 133–166.
Centi, G.; Perathoner, S. From Green to Sustainable Industrial Chemistry. In Sustainable
Industrial Chemistry; Cavani, F., Centi, G., Perathoner, S., Trifiró, F., Eds.; WILEY-
VCH: Weinheim, 2009; p 599.
(9)
Selva, M.; Perosa, A. Green Chemistry Metrics: A Comparative Evaluation of Dimethyl
Carbonate, Methyl Iodide, Dimethyl Sulfate and Methanol as Methylating Agents.
Green Chem. 2008, 10, 457.
(10) Li, Q.; Chen, J.; Fan, L.; Kong, X.; Lu, Y. Progress in Electrolytes for Rechargeable Li-
Based Batteries and Beyond. Green Energy Environ. 2016, 1, 18–42.
(11) Nitta, N.; Wu, F.; Lee, J. T.; Yushin, G. Li-Ion Battery Materials: Present and Future.
Mater. Today 2015, 18, 252–264.
(12) UBE Industries. Ube Industries Licenses DMC Technology and Agrees to Establish
21
ACS Paragon Plus Environment

ACS Catalysis
Page 22 of 26
1
2
3
4
Joint
Venture
for
High-Purity
DMC
http://www.ube-
5
6
ind.co.jp/ube/en/news/2015/20160316_01.html (accessed Mar 12, 2018).
7
8
9
(13) Di, M. N.; Fusi, C.; Rivetti, F.; Sasselli, G. Process for Producing Dimethyl Carbonate.
European Patent EP0460732A1, 1991.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
(14) Miyazaki, H.; Shiomi, Y.; Fujitus, S.; Masunaga, K.; Yanagisawa, H. Process for the
Preparation of Oxalic Acid Diesters. United States Patent 4384133, 1982.
(15) Santos, B. a. V.; Silva, V. M. T. M.; Loureiro, J. M.; Rodrigues, A. E. Review for the
Direct Synthesis of Dimethyl Carbonate. ChemBioEng Rev. 2014, 1, 214–229.
(16) Otsuka, K.; Yagi, T.; Yamanaka, I. Synthesis of Dimethyl Carbonate by Electrolytic
Carbonylation of Methanol in the Gas Phase. Chem. Soc. Japan 1994, No. 3, 495–498.
(17) Otsuka, K.; Yagi, T.; Yamanaka, I. Dimethyl Carbonate Synthesis by Electrolytic
Carbonylation of Methanol in the Gas Phase. Electrochim. Acta 1994, 39, 2109–2115.
(18) Pacheco, M. A.; Marshall, C. L. Review of Dimethyl Carbonate (DMC) Manufacture
and Its Characteristics as a Fuel Additive. Energy & Fuels 1997, 11, 2–29.
(19) Funakawa, A.; Yamanaka, I.; Otsuka, K. Active Control of Methanol Carbonylation
Selectivity over Au/Carbon Anode by Electrochemical Potential. J. Phys. Chem. B 2005,
109, 9140–9147.
(20) Funakawa, A.; Yamanaka, I.; Otsuka, K. High Efficient Electrochemical Carbonylation
of Methanol to Dimethyl Carbonate by Br2∕Br− Mediator System over Pd∕C Anode. J.
Electrochem. Soc. 2006, 153, D68.
(21) Yamanaka, I.; Funakawa, A.; Otsuka, K. Selective Carbonylation of Methanol to
Dimethyl Carbonate by Gas–Liquid–Solid-Phase Boundary Electrolysis. Chem. Lett.
22
ACS Paragon Plus Environment

Page 23 of 26
ACS Catalysis
1
2
3
4
2002, 2, 448–448.
5
6
7
8
9
(22) Yamanaka, I.; Funakawa, A.; Otsuka, K. Electrocatalytic Synthesis of DMC over the
Pd/VGCF Membrane Anode by Gas-Liquid-Solid Phase-Boundary Electrolysis. J.
Catal. 2004, 221, 110–118.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
(23) Funakawa, A.; Yamanaka, I.; Takenaka, S.; Otsuka, K. Selectivity Control of
Carbonylation of Methanol to Dimethyl Oxalate and Dimethyl Carbonate over Gold
Anode by Electrochemical Potential. J. Am. Chem. Soc. 2004, 126, 5346–5347.
(24) Figueiredo, M. C.; Trieu, V.; Eiden, S.; Koper, M. T. M. M. Spectro-Electrochemical
Examination of the Formation of Dimethyl Carbonate from CO and Methanol at
Different Electrode Materials. J. Am. Chem. Soc. 2017, 139, 14693–14698.
(25) Otsuka, K. Electrolytic Carbonylation of Methanol over the CuCl2 Anode in the Gas
Phase. J. Electrochem. Soc. 1995, 142, 130.
(26) Cipris, D.; Mador, I. L. Anodic Synthesis of Organic Carbonates. J. Electrochem. Soc.
1978, 125, 1954–1959.
(27) Heli, H.; Jafarian, M.; Mahjani, M. G.; Gobal, F. Electro-Oxidation of Methanol on
Copper in Alkaline Solution. Electrochim. Acta 2004, 49, 4999–5006.
(28) Abd El Haleem, S. M.; Ateya, B. G. Cyclic Voltammetry of Copper in Sodium
Hydroxide Solutions. J. Electroanal. Chem 1981, 117, 309–319.
(29) Brooksby, P. A.; McQuillan, A. J. Oxidative IR Spectroelectrochemistry of Copper in
Methanol Containing Carbon Monoxide. Langmuir 2014, 30, 14337–14342.
(30) Marshall, A. T.; Golovko, V.; Padayachee, D. Influence of Gold Nanoparticle Loading
in Au/C on the Activity towards Electrocatalytic Glycerol Oxidation. Electrochim. Acta
23
ACS Paragon Plus Environment

ACS Catalysis
Page 24 of 26
1
2
3
4
2015, 153, 370–378.
5
6
7
8
9
(31) Housmans, T. H. M.; Wonders, A. H.; Koper, M. T. M. Structure Sensitivity of Methanol
Electrooxidation Pathways on Platinum: An on-Line Electrochemical Mass
Spectrometry Study. J. Phys. Chem. B 2006, 110, 10021–10031.
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
(32) Hori, Y.; Koga, O.; Yamazaki, H.; Matsuo, T. Infrared Spectroscopy of Adsorbed CO
and Intermediate Species in Electrochemical Reduction of CO2 to Hydrocarbons on a
Cu Electrode. Electrochim. Acta 1995, 40, 2617–2622.
(33) Shaw, S. K.; Berná, A.; Feliu, J. M.; Nichols, R. J.; Jacob, T.; Schiffrin, D. J. Role of
Axially Coordinated Surface Sites for Electrochemically Controlled Carbon Monoxide
Adsorption on Single Crystal Copper Electrodes. Phys. Chem. Chem. Phys. 2011, 13,
5242.
(34) Salimon, J.; Hernández-Romero, R. M.; Kalaji, M. The Dynamics of the Conversion of
Linear to Bridge Bonded CO on Cu. J. Electroanal. Chem. 2002, 538–539, 99–108.
(35) Hernández-R, R. M.; Kalaji, M. Electrochemical Reactions of CO on Polycrystalline
Copper Electrodes. J. Electroanal. Chem. 1997, 434, 209–215.
(36) Rodriguez, P.; Kwon, Y.; Koper, M. T. M. The Promoting Effect of Adsorbed Carbon
Monoxide on the Oxidation of Alcohols on a Gold Catalyst. Nat. Chem. 2012, 4, 177–
182.
(37) Ogura, T. Complex Formation of Copper(I) Perchlorate with Ethylene or Carbon
Monoxide in Water and Isolation of Related Complexes. Inorg. Chem. 1976, 15, 2301–
2303.
(38) Kuhl, K. P.; Cave, E. R.; Abram, D. N.; Jaramillo, T. F. New Insights into the
24
ACS Paragon Plus Environment

Page 25 of 26
ACS Catalysis
1
2
3
4
5
6
Electrochemical Reduction of Carbon Dioxide on Metallic Copper Surfaces. Energy
Environ. Sci. 2012, 5, 7050.
7
8
9
(39) Arán-Ais, R. M.; Gao, D.; Roldan Cuenya, B. Structure- and Electrolyte-Sensitivity in
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
CO2
Electroreduction.
Acc.
Chem.
Res.
2018,
https://pubs.acs.org/doi/10.1021/acs.accounts.8b00360.
(40) Iwasita, T.; Nart, F. C. In Situ Infrared Spectroscopy At Electrochemical Interfaces.
Prog. Surf. Sci. 1997, 55, 271–340.
25
ACS Paragon Plus Environment

ACS Catalysis
Page 26 of 26
1
2
3
4
Table of Contents Graphic
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
26
ACS Paragon Plus Environment