Synthesis and antiviral activity of new phosphonobutoxypurines

DOI: 10.1016/0960-894X(96)00400-3

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2215 - 2218 (1996)

Update date:2022-08-10

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Authors:

Harnden, Michael R.

Serafinowska, Halina T.

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Article abstract of DOI:10.1016/0960-894X(96)00400-3

A series of new 9-(4-phosphonobutoxy)purines was synthesized and evaluated as antiviral agents. 9-(4-Phosphonobutoxy)guanine displayed potent and selective activity against HIV-1 in peripheral blood lymphocytes.

Full text of DOI:10.1016/0960-894X(96)00400-3

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