Detecting ricin: Sensitive luminescent assay for ricin A-chain ribosome depurination kinetics

DOI: 10.1021/ac8026433

Source and publish data:

Analytical Chemistry p. 2847 - 2853 (2009)

Update date:2022-08-30

Topics:

Authors:

Sturm, Matthew B.

Schramm, Vern L.

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Article abstract of DOI:10.1021/ac8026433

Ricin is a family member of the lethal ribosome-inactivating proteins (RIP) found in plants. Ricin toxin A-chain (RTA) from castor beans catalyzes the hydrolytic depurination of a single base from a GAGA tetraloop of eukaryotic rRNA to release a single ad

Full text of DOI:10.1021/ac8026433

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