A two-steps benzotriazole-assisted synthesis of 3-amino-2-ethoxycarbonyl imidazo [1,2-a] pyridines and related compounds

DOI: 10.1016/0040-4039(96)00132-3

Source and publish data:

Tetrahedron Letters p. 1787 - 1790 (1996)

Update date:2022-08-12

Topics:

Authors:

Moutou, Jean-Luc

Schmitt, Martine

Collot, Valerie

Bourguignon, Jean-Jacques

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Article abstract of DOI:10.1016/0040-4039(96)00132-3

Reaction of primary heterocyclic amidines with benzotriazole and ethyl glyoxylate or ethyl glyoxylate equivalents afforded the corresponding α-benzotriazolyl-α-amidino esters which, upon treatment potassium cyanide yielded the corresponding 3-amino-2-ethoxycarbonyl imidazo [1,2-a] pyridines and related compounds.

Full text of DOI:10.1016/0040-4039(96)00132-3

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