Synthesis of (±)-5,6,7-trinor-4,8-inter-m-phenylene PGI2

DOI: 10.1016/S0040-4039(00)97656-1

Source and publish data:

Tetrahedron Letters p. 4489 - 4492 (1990)

Update date:2022-08-31

Topics:

Authors:

Ohno, Kiyotaka

Nishiyama, Hisao

Nagase, Hiroshi

Matsumoto, Kazuhisa

Ishikawa, Mamoru

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Article abstract of DOI:10.1016/S0040-4039(00)97656-1

A stable and potent analog of prostacyclin, the titled compound, and its derivative were synthesized from readily available 1,4-dibromocyclopentene via 5-(4-tetrahydropyranyloxybutyl)cyclopenta[b]benzofuran 7.

Full text of DOI:10.1016/S0040-4039(00)97656-1

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Product name:Benzene, 1,1'-[4-cyclopentene-1,3-diylbis(oxy)]bis[2,6-dibromo-, cis-

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