Fluorous synthesis of substituted sclerotigenin library

DOI: 10.1021/cc9001636

Source and publish data:

Journal of Combinatorial Chemistry p. 125 - 128 (2010)

Update date:2022-08-03

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Authors:

Lu, Yimin

Nagashima, Tadamichi

Miriyala, Bruhaspathv

Conde, Joanne

Zhang, Wei

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Article abstract of DOI:10.1021/cc9001636

A fluorous linker-assisted synthetic protocol has been developed for preparation of sclerotigenin-type benzodiazepine-quinazolinone library containing 144 analogues. Amide coupling of fluorous trimethoxybenzyl (TMB)-protected amino esters with anthranilic

Full text of DOI:10.1021/cc9001636

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