Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Linoleic acid

Related Products

Hot Products

Name

Linoleic acid

EINECS 200-470-9
CAS No. 60-33-3 Density 0.912 g/cm3
PSA 37.30000 LogP 5.88450
Solubility insoluble in water Melting Point -5 °C
Formula C18H32O2 Boiling Point 360.552 °C at 760 mmHg
Molecular Weight 280.451 Flash Point 272.976 °C
Transport Information N/A Appearance Colorless to straw colored liquid
Safety 26-24/25-36 Risk Codes 36
Molecular Structure Molecular Structure of 60-33-3 (Linoleic acid) Hazard Symbols IrritantXi
Synonyms

9,12-Octadecadienoicacid (Z,Z)-;Linoleic acid (8CI);(9Z,12Z)-9,12-Octadecadienoic acid;(Z,Z)-9,12-Octadecadienoic acid;9,12-Octadecadienoic acid, (Z,Z)-;9-cis,12-cis-Linoleic acid;9Z,12Z-Linoleic acid;9Z,12Z-Octadecadienoic acid;Emersol 315;Extra Linoleic 90;all-cis-9,12-Octadecadienoic acid;cis,cis-Linoleic acid;cis-9,cis-12-Octadecadienoic acid;cis-D9,12-Octadecadienoic acid;

Article Data 102

Linoleic acid Synthetic route

19836-71-6

linoleic nitrile

60-33-3

linoleic acid

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water Heating;81%
141-22-0

Ricinoleic acid

A

544-70-7, 544-71-8, 872-23-1, 1839-11-8, 2540-56-9

cis-9,trans-11-octadecadienoic acid

B

544-70-7, 544-71-8, 872-23-1, 1839-11-8, 2540-56-9

trans-9,trans-11-octadecadienoic acid

C

1072-36-2, 2420-44-2, 2420-56-6, 7307-45-1, 22880-03-1

trans-10,cis-12-octadecadienoic acid

D

60-33-3

linoleic acid

E

1072-36-2

10E,12E-octadecadienoic acid

Conditions
ConditionsYield
With 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; potassium hydroxide In ethylene glycol at 180℃; for 0.5h; Microwave irradiation;A n/a
B n/a
C n/a
D 22%
E n/a
F 46%
With 1-n-butyl-3-methylimidazolim bromide; potassium hydroxide In ethylene glycol at 180℃; for 0.5h; Microwave irradiation;A n/a
B n/a
C n/a
D 12%
E n/a
F 9%
soybean oil, refined, bleached and deodorized

soybean oil, refined, bleached and deodorized

A

trans fatty acid; mixture of

trans fatty acid; mixture of

B

112-80-1

cis-Octadecenoic acid

C

60-33-3

linoleic acid

D

463-40-1

(9Z,12Z,15Z)-octadeca-9-12,15-trienoic acid

E

57-11-4

stearic acid

Conditions
ConditionsYield
With hydrogen; mineral malachite at 165℃; under 3102.97 Torr; for 4h; Conversion of starting material;A 16.23%
B 37.82%
C 41.48%
D 2.92%
E 5.39%
Conditions
ConditionsYield
With potassium hydroxide
2012-14-8

9,12-octadecadiynoic acid

60-33-3

linoleic acid

Conditions
ConditionsYield
With quinoline; Lindlar's catalyst; Petroleum ether Hydrogenation;
With pyridine; palladium on activated charcoal; Lindlar's catalyst Hydrogenation;
Methyl linoleate

Methyl linoleate

60-33-3

linoleic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol
With water; sodium hydroxide In methanol for 1h; Heating;
1794-89-4, 54324-50-4, 56846-03-8, 56846-04-9

rac-(9R,10R,12S,13S)-9,10,12,13-Tetrabromostearic acid

60-33-3

linoleic acid

Conditions
ConditionsYield
With tetrabutylammonium tetrafluoroborate In N,N-dimethyl-formamide -1.4 V (vs. SCE) at a mercury pool (divided cell); Yield given;
119520-51-3

(9Z,12Z)-N-(pyridin-3-yl)octadeca-9,12-dienamide

60-33-3

linoleic acid

Conditions
ConditionsYield
With carbon disulfide; n-butyllithium; benzeneseleninic acid; 1,1,1,3,3,3-hexamethyl-disilazane 1.) THF, hexane, -20 deg C, 30 min, 2.) THF, rt, 3.) THF, rt, 5 h; Yield given. Multistep reaction;
(2S)-1-O-(9Z,12Z)-octadecadienoyl-2-O-(7Z,10Z)-hexadecadienoyl-3-O-α-D-galactopyranosyl-(1->6)-β-D-galactopyranosyl-sn-glycerol

(2S)-1-O-(9Z,12Z)-octadecadienoyl-2-O-(7Z,10Z)-hexadecadienoyl-3-O-α-D-galactopyranosyl-(1->6)-β-D-galactopyranosyl-sn-glycerol

A

60-33-3

linoleic acid

B

(7Z,10Z)-Hexadeca-7,10-dienoic acid (R)-1-hydroxymethyl-2-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-2-yloxy]-ethyl ester

Conditions
ConditionsYield
With boric acid-borax buffer; Lipase type XI; Triton X-100 at 38℃; for 1h;
17-bromo-heptadeca-6c,9c-diene

17-bromo-heptadeca-6c,9c-diene

60-33-3

linoleic acid

Conditions
ConditionsYield
With diethyl ether; magnesium anschliessend mit Kohlendioxid;

Linoleic acid Consensus Reports

Reported in EPA TSCA Inventory.

Linoleic acid Specification

The CAS registry number of Linoleic acid is 60-33-3. With the EINECS registry number 200-470-9, its systematic name is (9Z,12Z)-octadeca-9,12-dienoic acid. It is a colorless liquid at room temperature. And it belongs to one of the two families of essential fatty acids that humans and other animals must ingest for good health. In addition, it is used in making soaps, emulsifiers, and quick-drying oils. Besides, it has become increasingly popular in the beauty products industry because of its beneficial properties on the skin.

Physical properties about this chemical are: (1)ACD/LogP: 7.02; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 6.219; (4)ACD/LogD (pH 7.4): 4.424; (5)ACD/BCF (pH 5.5): 20180.996; (6)ACD/BCF (pH 7.4): 323.607; (7)ACD/KOC (pH 5.5): 24903.602; (8)ACD/KOC (pH 7.4): 399.335; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 14; (12)Polar Surface Area: 37.3 Å2; (13)Index of Refraction: 1.478; (14)Molar Refractivity: 87.121 cm3; (15)Molar Volume: 307.512 cm3; (16)Polarizability: 34.537 ×10-24cm3; (17)Surface Tension: 34.355 dyne/cm; (18)Density: 0.912 g/cm3; (19)Flash Point: 272.976 °C; (20)Enthalpy of Vaporization: 66.597 kJ/mol; (21)Boiling Point: 360.552 °C at 760 mmHg.

Preparation of Linoleic acid: it can be prepared by octadeca-9c,12c-dienenitrile. This reaction will need reagent NaOH and solvents ethanol and H2O. The yield is about 81% by heating.

Linoleic acid can be prepared by octadeca-9c,12c-dienenitrile

Uses of Linoleic acid: it can be used to get octadecanoic acid. This reaction will need reagent H2, catalyst Rhodium chloride tri(triphenylphosphine-meta-trisulfonate) and solvent H2O. The reaction time is 18 hours with ambient temperature. The yield is about 95%.

Linoleic acid can be used to get octadecanoic acid

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes. During using it, wear suitable protective clothing and avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: CCCCC/C=C\C/C=C\CCCCCCCC(=O)O
(2)Std. InChI: InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-
(3)Std. InChIKey: OYHQOLUKZRVURQ-HZJYTTRNSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 280mg/kg (280mg/kg)   Yakugaku Zasshi. Journal of Pharmacy. Vol. 104, Pg. 793, 1984.
mouse LD50 oral > 50gm/kg (50000mg/kg)   United States Patent Document. Vol. #3728459,
rat LD50 intraperitoneal > 50gm/kg (50000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 327, 1970.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 60-33-3