Tyrosine

Base Information Edit

Chemical Name:Tyrosine
CAS No.:60-18-4
Deprecated CAS:140-43-2,1991-85-1,46209-14-7,55520-40-6,1207451-88-4,2416148-26-8,1207451-88-4,46209-14-7,55520-40-6
Molecular Formula:C9H11NO3
Molecular Weight:181.191
Hs Code.:H11NO3 MOL WT. 181.19
European Community (EC) Number:200-460-4
UNII:42HK56048U
DSSTox Substance ID:DTXSID1023730
Nikkaji Number:J9.173A
Wikipedia:Tyrosine
Wikidata:Q188017,Q27115106
NCI Thesaurus Code:C915
RXCUI:10962
Metabolomics Workbench ID:37107
ChEMBL ID:CHEMBL925
Mol file:60-18-4.mol

Synonyms:L Tyrosine;L-Tyrosine;para Tyrosine;para-Tyrosine;Tyrosine;Tyrosine, L isomer;Tyrosine, L-isomer

Suppliers and Price of Tyrosine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Tyrosine
200ul
$ 505.00

Usbiological
Tyr
48Tests
$ 588.00

Usbiological
TYR
48Tests
$ 588.00

Usbiological
Tyrosine
200ul
$ 443.00

TRC
L-Tyrosine
100mg
$ 55.00

TCI Chemical
L-(-)-Tyrosine >98.5%(T)
100g
$ 73.00

TCI Chemical
L-(-)-Tyrosine >98.5%(T)
25g
$ 28.00

TCI Chemical
L-(-)-Tyrosine >98.5%(T)
500g
$ 310.00

SynQuest Laboratories
L-Tyrosine 99.5%
1 kg
$ 136.00

SynQuest Laboratories
L-Tyrosine 99.5%
100 g
$ 23.00

Total 389 raw suppliers

Chemical Property of Tyrosine Edit

Chemical Property:

Appearance/Colour:White to off-white powder
Melting Point:>300 °C (dec.)(lit.)
Refractive Index:-12 ° (C=5, 1mol/L HCl)
Boiling Point:385.163 °C at 760 mmHg
PKA:2.2(at 25℃)
Flash Point:186.74 °C
PSA：83.55000
Density:1.334 g/cm³
LogP:1.04690
Storage Temp.:Store at RT.
Solubility.:1 M HCl: 25 mg/mL
Water Solubility.:0.45 g/L (25 ºC)
XLogP3:-2.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:181.07389321
Heavy Atom Count:13
Complexity:176

Purity/Quality:

98% ^*data from raw suppliers

Tyrosine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38-40
Safety Statements: 26-36-37/39-22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Biological Agents -> Amino Acids and Derivatives
Canonical SMILES:C1=CC(=CC=C1CC(C(=O)O)N)O
Isomeric SMILES:C1=CC(=CC=C1C[C@@H](C(=O)O)N)O
Recent ClinicalTrials:Contribution of L-Tyrosine to Human Decision Making in Stressful Situations
Recent NIPH Clinical Trials:Effect of immunotherapy on oncological and patientst reported outcomes in patients with metastatic renal cell cancer
Chemical Properties and Configuration L-tyrosine is an optically active form of tyrosine with an L-configuration. It is a versatile amino acid precursor used in the production of various valuable aromatics and chemical compounds.
Role in Biomarker Detection Amino acids like tyrosine have gained attention as potential biomarkers for various diseases. Metabolomic methods are commonly used to detect tyrosine and other amino acids, but they can be costly and time-consuming. Alternatively, electrochemical sensors offer a simple, cost-effective, and highly sensitive detection method.
Production and Demand Tyrosine is in high demand globally due to its versatility in the production of valuable compounds. Worldwide production averages around 165 metric tons per year.
Essentiality and Dietary Supplementation Tyrosine is classified as a non-essential amino acid for humans as it can be naturally derived from phenylalanine. However, for patients with phenylketonuria (PKU) disorder, tyrosine becomes essential due to a deficiency in the hepatic enzyme for converting phenylalanine to tyrosine. Tyrosine is commonly used as a constituent in dietary supplements, particularly for its efficacy in stimulating brain activity.
Substrate Specificity and Biosynthetic Pathways In biosynthetic pathways, phenylalanine or tyrosine are typically used as substrates due to the substrate specificity of ammonia-lyase. Preliminary investigations have explored the simultaneous utilization of phenylalanine and tyrosine by expressing a tyrosine ammonia lyase in strains harboring the phenylalanine pathway, leading to enhanced p-coumaric acid production despite the low efficiency of tyrosine ammonia lyase.

Technology Process of Tyrosine

There total 323 articles about Tyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%