Ethanol, 2-(ethylmethylamino)-

Base Information

• Chemical Name: Ethanol, 2-(ethylmethylamino)-
• CAS No.: 2893-43-8
• Molecular Formula: C₅H₁₃NO
• Molecular Weight: 103.164
• DSSTox Substance ID: DTXSID10183131
• Nikkaji Number: J13.772C
• Wikidata: Q83053854
• Mol file: 2893-43-8.mol

Synonyms:2893-43-8;ETHANOL, 2-(ETHYLMETHYLAMINO)-;Riker #566;2-[ethyl(methyl)amino]ethan-1-ol;2-[ethyl(methyl)amino]ethanol;2-(Ethylmethylamino)ethanol;n-ethyl-n-methylethanolamine;2-(N-METHYLETHYLAMINO)ETHANOL;BRN 1731982;MFCD00045978;n-methyl-n-ethylethanolamine;Riker No.566;SCHEMBL97389;DTXSID10183131;AKOS003083883;LS-66768;NS-01003;FT-0766618;F79766

Chemical Property of Ethanol, 2-(ethylmethylamino)-

Chemical Property:

• Vapor Pressure: 2.4mmHg at 25°C
• Boiling Point: 141.3°Cat760mmHg
• Flash Point: 35.5°C
• PSA: 23.47000
• Density: 0.89g/cm³
• LogP: -0.06960
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 103.099714038
• Heavy Atom Count: 7
• Complexity: 39.1

Purity/Quality:

98%min ^*data from raw suppliers

2-[ethyl(methyl)amino]ethan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(C)CCO

Technology Process of Ethanol, 2-(ethylmethylamino)-

There total 9 articles about Ethanol, 2-(ethylmethylamino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

N-Ethylmethylamine (624-78-2) + 2-chloro-ethanol (107-07-3) → 2-(N-ethyl-N-methylamino)ethanol (2893-43-8)

Guidance literature:

With potassium carbonate; In acetonitrile; for 24h; Reflux;

Reference yield: 48.0%

(2-hydroxyethyl)(methyl)amine (109-83-1) + ethyl bromide (74-96-4) → 2-(N-ethyl-N-methylamino)ethanol (2893-43-8)

Guidance literature:

at 0 - 20 ℃; for 150h;

DOI:10.1071/CH14217

Reference yield:

methanol (67-56-1) + 2-(Ethylamino)ethanol (110-73-6) → 2-(N-ethyl-N-methylamino)ethanol (2893-43-8)

Guidance literature:

With Cs-P-Si mixed-oxide; at 300 ℃; under 61504.9 Torr;

DOI:10.1002/1521-3773(20020916)41:18<3476::AID-ANIE3476>3.0.CO;2-5

upstream raw materials:

oxirane

N-Ethylmethylamine

2,2'-(phenylimino)bis[ethanol]

formaldehyd

Downstream raw materials:

2-chloro-N-ethyl-N-methylethanamine hydrochloride

1-Phenyl-cyclopentan-1-carbonsaeure-<2-(methyl-ethylamino)-ethylester>

2-(Ethylmethylamino)ethyl bromide

Refernces

• 1、 Yang, Qinping,Dong, Yanliang,Wang, Xuanyu,Lin, Zhihao,Yan, Mingyu,Wang, Weiwei,Dong, Anjie,Zhang, Jianhua,Huang, Pingsheng,Wang, Changrong. "pH-Sensitive Polycations for siRNA Delivery: Effect of Asymmetric Structures of Tertiary Amine Groups". . . Retrieved 2021.
• 2、 -. "DIALKYLAMINO ALKYL ESTERS OF PIVAGABINE AS MEDICAMENTS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS". Page/Page column 75-76. . Retrieved 2008/12/06.