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Sarcosine

Base Information Edit
  • Chemical Name:Sarcosine
  • CAS No.:107-97-1
  • Deprecated CAS:783292-49-9
  • Molecular Formula:C3H7NO2
  • Molecular Weight:89.0941
  • Hs Code.:29224995
  • European Community (EC) Number:203-538-6,270-156-4,636-764-2
  • NSC Number:118114
  • UNII:Z711V88R5F
  • DSSTox Substance ID:DTXSID1047025
  • Nikkaji Number:J5.067I
  • Wikipedia:Sarcosine
  • Wikidata:Q414157
  • NCI Thesaurus Code:C113501
  • RXCUI:1362906
  • Metabolomics Workbench ID:37173
  • ChEMBL ID:CHEMBL304383
  • Mol file:107-97-1.mol
Sarcosine

Synonyms:Sarcosine(8CI);(Methylamino)acetic acid;(Methylamino)ethanoic acid;2-(Methylamino)acetic acid;Acetic acid, (methylamino)-;Methylglycine;N-Methylaminoaceticacid;N-Methylglycine;Sarcosin;Sarcosinic acid;

Suppliers and Price of Sarcosine
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Sarcosine
  • 250g
  • $ 620.00
  • TRC
  • Sarcosine
  • 25g
  • $ 95.00
  • Tocris
  • Sarcosine
  • 50
  • $ 56.00
  • TCI Chemical
  • Sarcosine >98.0%(T)
  • 100g
  • $ 31.00
  • TCI Chemical
  • Sarcosine >98.0%(T)
  • 25g
  • $ 15.00
  • TCI Chemical
  • Sarcosine >98.0%(T)
  • 500g
  • $ 124.00
  • Sigma-Aldrich
  • Sarcosine for synthesis. CAS 107-97-1, EC Number 203-538-6, chemical formula CH NHCH COOH., for synthesis
  • 8076669010
  • $ 1090.00
  • Sigma-Aldrich
  • Sarcosine for synthesis
  • 10 kg
  • $ 1045.25
  • Sigma-Aldrich
  • Sarcosine BioXtra
  • 25g
  • $ 151.00
  • Sigma-Aldrich
  • Sarcosine 98%
  • 500g
  • $ 149.00
Total 221 raw suppliers
Chemical Property of Sarcosine Edit
Chemical Property:
  • Appearance/Colour:white crystalline powder 
  • Vapor Pressure:0.184mmHg at 25°C 
  • Melting Point:208-212 °C (dec.)(lit.) 
  • Refractive Index:1.431 
  • Boiling Point:195.1 °C at 760 mmHg 
  • PKA:2.21(at 25℃) 
  • Flash Point:71.8 °C 
  • PSA:49.33000 
  • Density:1.093 g/cm3  
  • LogP:-0.31870 
  • Storage Temp.:Store at RT. 
  • Sensitive.:Hygroscopic 
  • Solubility.:H2O: 1 M at 20 °C 
  • Water Solubility.:1480 g/L (20 ºC) 
  • XLogP3:-2.8
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:2
  • Exact Mass:89.047678466
  • Heavy Atom Count:6
  • Complexity:52.8
Purity/Quality:

99% *data from raw suppliers

Sarcosine *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi 
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 24/25-36-26 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Chemical Classes:Biological Agents -> Amino Acids and Derivatives
  • Canonical SMILES:CNCC(=O)O
  • Recent ClinicalTrials:Effect of Sarcosine on Symptomatology, Quality of Life, Oxidative Stress and Glutamatergic Parameters in Schizophrenia
  • General Description Sarcosine, also known as N-methylglycine, is a naturally occurring amino acid derivative that serves as a key precursor in the synthesis of N-nitroso derivatives, which are studied for their potential carcinogenic properties. These derivatives may form in the human stomach from dietary nitrites and amino acids, raising concerns about their role in carcinogenesis. Sarcosine-derived N-nitrosamino acids are characterized as colorless crystalline solids with high solubility in water and organic solvents, and they can undergo decarboxylation under alkaline conditions to yield toxic and carcinogenic N-nitrosamines. This highlights the importance of understanding its chemical behavior in biological contexts.
Technology Process of Sarcosine

There total 105 articles about Sarcosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Refernces Edit

The preparation and properties of some nitrosamino acids

10.1016/S0040-4020(01)93166-7

The research investigates the synthesis and properties of N-nitroso derivatives of several amino acids. Sarcosine, azetidine-2-carboxylic acid, hydroxyproline, and pipecolic acid play crucial roles as the primary precursors for the synthesis of their respective N-nitroso derivatives. These derivatives are of significant interest due to their potential carcinogenic properties and their possible formation in the human stomach from dietary nitrites and amino acids. The study aims to understand the formation and characteristics of these nitrosamino acids, which could potentially be relevant to the occurrence of human cancer due to their possible formation in the mammalian stomach from dietary nitrites and amino acids. The researchers prepared these compounds and characterized them using various analytical techniques such as NMR spectroscopy, mass spectrometry, and UV absorption spectroscopy. They found that these compounds are colorless crystalline solids with high yields and are highly soluble in water and most organic solvents. The study also explored the conformational preferences of these compounds in the crystalline state and their behavior in different solvents. The findings suggest that these nitrosamino acids can decarboxylate in dilute alkali to form N-nitrosamines, which are known to be toxic and carcinogenic. The research concludes that the properties of these compounds could have significant implications for understanding the potential carcinogenic activity of nitrosamino acids formed in the human stomach.

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