2-Chloro-1,1-difluoroethylene

Base Information

• Chemical Name: 2-Chloro-1,1-difluoroethylene
• CAS No.: 359-10-4
• Molecular Formula: C2HClF2
• Molecular Weight: 98.4797
• Hs Code.: 2903799090
• European Community (EC) Number: 206-625-7
• UNII: QGF1P560AW
• DSSTox Substance ID: DTXSID3073898
• Nikkaji Number: J28.326F
• Wikidata: Q26841345
• Mol file: 359-10-4.mol

Synonyms:1,1-difluoro-2-chloroethylene;2-chloro-1,1-difluoroethene;2-chloro-1,1-difluoroethylene

Chemical Property of 2-Chloro-1,1-difluoroethylene

Chemical Property:

• Melting Point: -138.5 °C
• Boiling Point: -17.7 °C at 760 mmHg
• Flash Point: -75℃
• PSA: 0.00000
• Density: 1.274 g/cm³
• LogP: 1.96310
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 97.9734841
• Heavy Atom Count: 5
• Complexity: 45.6

Purity/Quality:

99.0%Min ^*data from raw suppliers

2-Chloro-1,1-difluoroethylene 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F
• Hazard Codes: F
• Statements: 10
• Safety Statements: 16

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Halogenated Aliphatics, Unsaturated
• Canonical SMILES: C(=C(F)F)Cl

Technology Process of 2-Chloro-1,1-difluoroethylene

There total 52 articles about 2-Chloro-1,1-difluoroethylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1,1,1-trifluoro-2-chloroethane (75-88-7) + 2,2,2-trifluoroethanol (75-89-8) → 1,1,1,2-tetrafluoroethane (811-97-2) + 1-Chloro-2,2-difluoroethene (359-10-4) + 1,1,1-trifluoro-2-(2,2,2-trifluoroethoxy)ethane (333-36-8)

Guidance literature:

With potassium hydroxide; at 250 ℃; for 13h; under 77520 Torr;

DOI:10.1016/S0022-1139(01)00469-9

Reference yield:

Trichloroethylene (79-01-6) → carbon tetrafluoride (75-73-0) + 1,1,1,2,2-pentafluoroethane (354-33-6) + 2,2,2-trifluoroethanol (420-46-2) + 1-chloro-2,2-difluoroethane (338-65-8) + 1,1,1,2-tetrafluoroethane (811-97-2) + 1,1,1-trifluoro-2-chloroethane (75-88-7) + 1,1,2,2-tetrafluoroethane (359-35-3) + 1-chloro-2-fluoroethylene (460-16-2) + 1-Chloro-2,2-difluoroethene (359-10-4) + Hexafluoroethane (76-16-4) + Chloropentafluoroethane (76-15-3) + 1,1,1,2-tetrafluoro-2-chloroethane (2837-89-0)

Guidance literature:

Trichloroethylene; With hydrogen fluoride; chromium - based fluorination catalyst; at 180 ℃;

Cr and In on graphite catalyst; at 180 ℃; for 4h; Inconel 600 type reactor;

Cr on active alumina catalyst; Product distribution / selectivity; Inconel 600 type reactor;

Reference yield:

1,1,1-trifluoro-2-chloroethane (75-88-7) → 1,1,1,2,2-pentafluoroethane (354-33-6) + 2,2,2-trifluoroethanol (420-46-2) + 1,1,1,2-tetrafluoroethane (811-97-2) + 1-Chloro-2,2-difluoroethene (359-10-4)

Guidance literature:

With hydrogen fluoride; chromium fluoride; Carbonyl fluoride; at 350 - 430 ℃; Further Variations:; Catalysts; Product distribution;

DOI:10.1016/S0022-1139(01)00453-5

upstream raw materials:

1,2-dichloro-1,1-difluoroethane

1,1-dichloro-2,2-difluoroethane

1,1,1-trifluoro-2,2-dichloroethane

1,1,2-trichloro-2,2-difluoroethane

Downstream raw materials:

2,2-difluoro-1-chloro-3-oxabutane

3-chloro-1,1,2,4,4-pentafluoro-4-iodo-but-1-ene

1,1,1-trifluoro-2-chloroethane

1,2-dichloro-1,1-difluoroethane

Refernces

• 1、 Sakka, Tetsuo,Furuya, Hiroyuki,Iwasaki, Matae,Ogata, Yukio. "Effects of Addition Gases on the IR Multiphoton Dissociation of Haloethanes". . p. 983 - 986. Retrieved 1995.
• 2、 Kim, Honggon,Kim, Hoon S.,Lee, Byung G.,Lee, Hyunjoo,Kim, Sehoon. "Effect of Megnesium Fluoride in Chromium-Magnesium Catalysts on the Fluorination Reaction of 1,1,1-Trifluoro-2-chloroethane". . p. 2383 - 2384. Retrieved 1995.
• 3、 Brunet,Boussand,Martin. "Properties of chromium (III) oxides involved in the catalytic gas phase fluorination of CF3CH2Cl". . p. 287 - 292. Retrieved 1997.
• 4、 Kemnitz,Niedersen. "Mechanistic aspects of the isomerization reactions of 1,1,2,2-tetrafluoroethane on a CFC-conditioned chromia catalyst". . p. 111 - 119. Retrieved 1996.
• 5、 Barrault, J.,Brunet, S.,Requieme, B.,Blanchard, M.. "Preparation of Substitutes for CFCs. Catalytic Properties of Chromia for Halogen Exchange involving Hydrogen Fluoride and Trifluorochloroethane". . p. 374 - 375. Retrieved 1993.
• 6、 Anilkumar,Burton, Donald J.. "Room temperature preparation of α-chloro-β,β- difluoroethenylzinc reagent (CF2CClZnCl) by the metallation of HCFC-133a (CF3CH2Cl) and a high yield one-pot synthesis of α-chloro-β,β-difluorostyrenes". . p. 835 - 843. Retrieved 2005.
• 7、 Holmes, Bert E.,Rakestraw, David J.. "An Experimental Estimate of the Threshold Barrier for the 1,2-Fluorine Atom Migration in 1,1,1-Trifluoromethylcarbene". . p. 2210 - 2216. Retrieved 1992.
• 8、 -. "Method for preparing ethyl difluorobromoacetate". Paragraph 0031-0032; 0037-0038; 0041-0042; 0045-0046; 0049. . Retrieved 2021/06/22.
• 9、 -. "METHOD FOR PRODUCING 1-CHLORO-2,2-DIFLUOROETHYLENE". Paragraph 0040-0043. . Retrieved 2018/10/03.