7-methylinosine

Base Information

• Chemical Name: 7-methylinosine
• CAS No.: 33763-06-3
• Molecular Formula: C₁₁H₁₄N₄O₅
• Molecular Weight: 282.256
• Mol file: 33763-06-3.mol

Synonyms:7-methylinosine

Chemical Property of 7-methylinosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-methylinosine

There total 1 articles about 7-methylinosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + methanol (67-56-1) + diethyl ether (60-29-7,927820-24-4) + acetone (67-64-1) + O2',O3',O5'-triacetyl-inosine (3181-38-2,7687-41-4,26289-76-9,28069-16-1,63248-71-5) → 7-methylinosine (33763-06-3) + 1-methylinosine (2140-73-0,55927-68-9) + 6-methoxypurine riboside (5746-29-2)

Guidance literature:

DOI:10.1021/ja00885a019

Reference yield: 73.0%

7-methylinosine (33763-06-3) + 4-amino-1H-imidazo<4,5-c>pyridine hydrochloride (4261-05-6) → 7-methyl-1,7-dihydro-purin-6-one (1006-08-2) + 3-deazaadenosine (6736-58-9)

Guidance literature:

With phosphate buffer; purine nucleoside phosphorylase; In water; at 25 ℃; for 48h; pH 7.0-7.4;

DOI:10.1021/jo00280a046

Reference yield: 57.0%

7-methylinosine (33763-06-3) + 1,2,4-triazole-3-carboxamide (3641-08-5) → 7-methyl-1,7-dihydro-purin-6-one (1006-08-2) + ribavirin (36791-04-5,66510-90-5)

Guidance literature:

With phosphate buffer; purine nucleoside phosphorylase; In water; at 25 ℃; for 48h; pH 7.4;

DOI:10.1021/jo00280a046

upstream raw materials:

diazomethane

methanol

diethyl ether

acetone

Downstream raw materials:

7-methyl-1,7-dihydro-purin-6-one

ribavirin

3-deazaadenosine

7-methyl-1,7-dihydro-purin-6-one