
Tetrahedron p. 6295 - 6302 (1997)
Update date:2022-09-26
Topics: Experimental terms Purine nucleosides
Lewandowska, Elzbieta
Neschadimenko, Vladimir
Wnuk, Stanislaw F.
Robins, Morris J.
Sodium naphthalenide effects removal of 2'-, 3'-, or 5'-O-tosyl groups from the sugar, and 2-, 6-, or 8-halogens from purine nucleosidcs. An improved tosyl protection strategy was developed for the synthesis of 9-(3-deoxy-3-fluoro-β-D-xylofuranosyl)adenine from 2',5'-di-O-tosyladenosine.
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Doi:10.1016/j.bmc.2018.02.016
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