Chemistry of Heterocyclic Compounds p. 1125 - 1129 (1991)
Update date:2022-08-05
Topics: Oxidation Reactivity Cyclization Condensation Spectral properties Chemical Structure 2-Substitution Biological Activity
Demina, L. M.
Gavrilov, M. Yu.
Vakhrin, M. I.
Konshin, M. E.
Cyclization of 2-(N-acetyl-N-arylamino)nicotinonitriles in the presence of dry HCl gave 1-aryl-2-methyl-4-oxo-1,4-dihydropyrido<2,3-d>pyrimidines.It was shown that they are acylated by acetic anhydride, aroyl chlorides, and phenyl isocyanate at the methyl
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