MIC90

The concentration required to inhibit 90% of bacterial growth.

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Synthesis Column chromatography QSAR (quantitative structure-activity relationship) Yield NMR spectroscopy Heterocyclic compounds Bioassay Molecular docking Recrystallization Mass spectrometry (MS) Solubility Pharmacophore Pyrazine Cytotoxicity binding affinity antimicrobial agents Minimum inhibitory concentration (MIC) Enzyme inhibition In vitro Testing In Vivo Testing Biological Evaluation Lead Optimization Zone of Inhibition Virtual Screening Resistance Structure-Activity Relationship (SAR) Antiviral Activity Enzyme Kinetics Drug Resistance Drug Repurposing MIC Determination Bioavailability Mycobacterium tuberculosis In Silico Studies Antitubercular Agents Metabolic Stability Antifungal Activity Scaffold Hopping Toxicity Profile Bioisosteres Heterocyclic compound N-Substituted Antimycobacterial Quinazolinones Docking simulation Gram-positive bacteria Gram-negative bacteria MIC assay Drug-likeness Antibacterial spectrum

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