Lead compounds may undergo further chemical optimization to enhance their potency, selectivity, and pharmacokinetic properties. Preclinical studies are conducted to assess their safety and efficacy in animal models before progressing to clinical trials.
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C20H14BrN3O5
(E)-2-(4-fluorostyryl)-3,4,5-trimethoxybenzaldehyde
1-cyclopropyl-3-(4-(5-(2,2-difluoropropyl)-6a-methyl-6-oxo-5,6,6a,7,9,10-hexahydro[1,4]oxazino[3,4-h]pteridin-2-yl)phenyl)urea
