Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents

Article abstract of DOI:10.1021/jm200639r

A new series of resveratrol analogues was designed, synthesized, and demonstrated to be tubulin polymerization inhibitors. Most of these compounds exhibited antiproliferative activity and inhibited in vitro tubulin polymerization effectively at concentrat

Full text of DOI:10.1021/jm200639r

Supporting information
Design and Synthesis of Resveratrol-based Nitrovinylstilbenes as
Antimitotic Agents
M. Amarnath Reddya#, Nishant Jain b#, Deepthi Yadaa, Chandan Kishore b, Vangala Janakiram
Reddyb , Anthony Addlagatta*b, Shasi V. Kalivendi*b, Bojja Sreedhar *a
aInorganic and Physical Chemistry Division and Centre for Chemical Biology, Indian Institute
b
of Chemical Technology (Council of Scientific and Industrial Research), Hyderabad 500607,
India.
# These authors made equal contribution to the work
Corresponding author Tel: +91-40-27191715; Fax: +91-40-27160921
E-mail: sreedharb@iict.res.in (B. Sreedhar), anthony@iict.res.in (A. Addlagatta)
kalivendi@iict.res.in (S. V. Kalivendi)
1. NMR Spectra
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