Journal of Medicinal Chemistry p. 6751 - 6760 (2011)
Update date:2022-08-05
Topics: Structure-Activity Relationship (SAR) Analysis Chemical Synthesis Biological Evaluation Literature Review and Target Identification In Vivo Efficacy Studies Mechanism of Action Studies Optimization and Preclinical Development Design of Nitrovinylstilbene Derivatives Pharmacokinetic and Toxicity Assessment Regulatory Approvals and Clinical Trials Scale-Up Production and Commercialization
Reddy, M. Amarnath
Jain, Nishant
Yada, Deepthi
Kishore, Chandan
Vangala, Janakiram Reddy
P. Surendra, Reddy
Addlagatta, Anthony
Kalivendi, Shasi V.
Sreedhar, Bojja
A new series of resveratrol analogues was designed, synthesized, and demonstrated to be tubulin polymerization inhibitors. Most of these compounds exhibited antiproliferative activity and inhibited in vitro tubulin polymerization effectively at concentrat
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(2011)