21299-15-0

Basic information

• Product Name: diethyl 2,4-dibenzoylpentanedioate
• CAS NO: 21299-15-0
• Molecular Formula: C₂₃H₂₄O₆
• Molecular Weight: 396.4331
• Mol File: 21299-15-0.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 540°C at 760 mmHg
• Flash Point: 233.6°C
• Density: 1.177g/cm³
• Vapor Pressure: 9.97E-12mmHg at 25°C
• Refractive Index: 1.544
• CAS DataBase Reference: diethyl 2,4-dibenzoylpentanedioate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2,4-dibenzoylpentanedioate(21299-15-0)
• EPA Substance Registry System: diethyl 2,4-dibenzoylpentanedioate(21299-15-0)

Safety Data

• Hazardous Substances Data: 21299-15-0(Hazardous Substances Data)

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 7087-68-5 N-ethyl-N,N-diisopropylamine 
• 1634-04-4 tert-butyl methyl ether 
• 50-00-0 formaldehyd 
• 109-73-9 N-butylamine 
• 74-89-5 methylamine 
• 22415-01-6 ethyl 2-benzoylacrylate 
• 68-12-2 N,N-dimethyl-formamide 
• 127-19-5 N,N-dimethyl acetamide 
• 7560-83-0 N-Methyldicyclohexylamine 
• 110-18-9 N,N,N,N,-tetramethylethylenediamine 
• 616-39-7 N,N-diethylnmethylamine 
• 98-86-2 acetophenone 
• 637-69-4 4-Methoxystyrene 

Downstream Products

• 93-89-0 benzoic acid ethyl ester 
• 6263-83-8 1,5-diphenyl-1,5-pentanedione 
• 1501-05-9 5-oxo-5-phenylvaleric acid 
• 70677-66-6 diethyl 2,6-diphenyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 1186485-64-2 4,4'-methylene-bis(2,5-diphenyl-1H-pyrazol-3(2H)-one) 
• 3558-69-8 2,6-diphenylpyridine 
• 854389-44-9 2,6-diphenyl-pyridine-3,5-dicarboxylic acid 

Relevant articles and documents

Selectfluor facilitated bridging of indoles to bis(indolyl)methanes using methyl: Tert -butyl ether as a new methylene precursor

A novel, green and efficient method is developed for the synthesis of methylene bridged bis(indolyl)methanes in good to excellent yields. The reaction employs methyl tert-butyl ether (MTBE) as the methylene source and selectfluor as an oxidizing agent. The scope and versatility of the methods have been successfully demonstrated with 48 examples. The metal-free transformation process is suitable for scale-up production. A selectfluor-promoted oxidative reaction mechanism is proposed based on the results of the experimental studies. This journal is

Diamine-mediated degradative dimerisation of Morita-Baylis-Hillman ketones

A degradative dimerisation of Morita-Baylis-Hillman ketones was observed in the presence of a primary diamine. The reaction proceeded swiftly to produce methylene-bridged 1,3-dicarbonyl compounds. A brief mechanistic investigation alluded to a retro-Mannich reaction as the key step of the transformation.

Metal-free synthesis of methylene-bridged bis-1,3-dicarbonyl compounds via oxidative C-C bond cleavage of tertiary aliphatic amines

A metal-free Bu4NI mediated oxidative reaction utilizing tertiary aliphatic amines and 1,3-dicarbonyl compounds for the synthesis of methylene-bridged bis-1,3-dicarbonyl compounds has been developed. This reaction involved an unexpected C-C bond cleavage of tertiary aliphatic amines. With this approach, the completely regioselective functionalization of β-carbon on tertiary amines was realized. This journal is the Partner Organisations 2014.