444-15-5

Basic information

• Product Name: DIALURIC ACID (100MGX5)
• Synonyms: 2,4,5,6-pyrimidinetetrol;2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-hydroxy-;5-hydroxy-2,4,6(1h,3h,5h)-pyrimidinetrione;5-hydroxy-barbituricaci;6(1h,3h,5h)-pyrimidinetrione,5-hydroxy-4;DIALURIC ACID (100MGX5);2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-hydroxy- (9CI);Dialuramic acid
• CAS NO: 444-15-5
• Molecular Formula: C₄H₄N₂O₄
• Molecular Weight: 144.08556
• EINECS: 207-145-0
• Product Categories: PYRIMIDINE;Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 444-15-5.mol

Chemical Properties

• Appearance: /
• Density: 1.696 g/cm³
• Refractive Index: 1.551
• CAS DataBase Reference: DIALURIC ACID (100MGX5)(CAS DataBase Reference)
• NIST Chemistry Reference: DIALURIC ACID (100MGX5)(444-15-5)
• EPA Substance Registry System: DIALURIC ACID (100MGX5)(444-15-5)

Safety Data

• Hazardous Substances Data: 444-15-5(Hazardous Substances Data)

Usage

Uses

Used in Nutritional Testing Industry:
DIALURIC ACID (100MGX5) is used as a testing agent for evaluating the nutritional vitamin E status in individuals. This helps in identifying any deficiencies or imbalances in vitamin E levels, which can lead to various health issues if left unaddressed.
Used in Research and Development:
DIALURIC ACID (100MGX5) is also utilized in research and development for studying the effects of vitamin E on various biological processes and its potential applications in the development of new drugs and therapies. This aids in advancing our understanding of vitamin E's role in maintaining health and preventing diseases.

InChI:InChI=1/C4H4N2O4/c7-1-2(8)5-4(10)6-3(1)9/h1,7H,(H2,5,6,8,9,10)

Upstream product

• 3914-34-9 6-amino-5-hydroxy-1H-pyrimidine-2,4-dione 
• 61066-33-9 pyrimidine-2,4,5,6(1H,3H)-tetraone 
• 52-90-4 L-Cysteine 
• 19186-12-0 dihydro-6-hydroxypyrimidine-2,4,5(3H)-trione 
• 124-46-9 guanidine hydrogen carbonate 
• 64-19-7 acetic acid 
• 511-67-1 5,5-dibromobarbituric acid 
• 69-93-2 uric Acid 
• 99985-14-5 5-benzyloxy-barbituric acid 
• 76-24-4 Alloxantin 
• 118-78-5 uramil 
• 7647-01-0 hydrogenchloride 
• 23090-99-5 diazo-(5-hydroxy-2,4,6-trioxo-hexahydro-pyrimidin-5-yl)-acetic acid ethyl ester 
• 7732-18-5 water 

Downstream Products

• 76-24-4 Alloxantin 
• 53039-86-4 5-Acetoxy-barbitursaeure 
• 78-84-2 isobutyraldehyde 
• 69-93-2 uric Acid 
• 97-59-6 Allantoin 
• 1852-18-2 tetrahydro-5-hydroxy-2(1H)-pyrimidinone 
• 504-07-4 5,6-dhydrouracil 
• 80-69-3 tartronic acid 
• 1780-40-1 2,4,5,6-tetrachloropyrimidine 
• 118-78-5 uramil 
• 106-34-3 quinhydrone 
• 64-18-6 formic acid 
• 7664-41-7 ammonia 
• 476-61-9 [5,5']bipyrimidinyl-2,4,6,2',4',6'-hexaone 

Relevant articles and documents

Catalytic strategies for sustainable oxidations

Several catalytic protocols for the oxidation of hydro-soluble substrates are presented that employ totally inorganic and robust polyoxometalate-based catalysts as well as porphyrin sensi-tizers, fullerenes and hybrid conjugates. Strategies for the imple-mentation of the system stability and efficiency are discussed.

Selective Reduction by 2-Amino-4-methylpyridine Borane and 2-Aminopyrimidine Borane

Stereo- and chemoselective reductions and synthetic utility of the title compounds are described.

The Radiolysis of Uracil in Oxygenated Aqueous Solutions. A Study by Product Analysis and Pulse Radiolysis

Hydroxyl radicals are generated by the radiolysis of N2O-O2 (4:1 v/v)-saturated aqueous solutions of uracil.They add to the 5,6-double bond of the substrate .These radicals are converted by oxygen into the corresponding peroxyl radicals (I) and (II), respectively.Peroxyl radical (I) undergoes a base-induced O2(1-.) elimination (kobs 8x1E3 s-1 at pH 10.5).As an intermediate 5-hydroxy-isopyrimidine is formed which rearranges into isobarbituric acid and adds water forming 5,6-dihydro-5,6-dihydroxyuracil.Competing with this base-induced reaction of radical (I) there is a bimolecular decay of radicals (I) and (II).These processes become predominant at low pH.For this reason a strong pH dependence of G (products) is observed.The major products are (G values at pH 3 and 10 in parentheses) 5,6-dihydroxy-5,6-dihydrouracil (1.1; 2.4), isobarbituric acid (0; 1.2), N-formyl-5-hydroxyhydantoin (1.6; 0.2), 5-hydroxybarbituric acid (0.9; 0.2). 5-Hydroxybarbituric acid is formed in its keto form.Its deprotonation (k 4.4 s-1) has been followed by pulse conductometry.Details of the reaction mechanism, e.g. the involvement of oxyl radicals in the bimolecular decay of (I) and (II), are discussed.

Reduction of Vicinal Tricarbonyl Compounds by Reduced Nicotinamide Adenine Dinucleotide Model and Electron-Transport Systems

The reduction of vicinal tricarbonyl compounds such as alloxan (A) and ninhydrin (NY) with 1-benzyl-1,4-dihydronicotinamide (BNAH; NADH model) was investigated.In the reduction of A with BNAH, the radical anion (A-.Py+) of A as the 1-benzyl-3-carbamoylpyridinium salt and the dialuric acid (D) was obtained by one-electron and two-electron reduction,respectively.Similarly,hydrindantin (HDT) and 2-hydroxy-1,3-indandione (HID) were also afforded in the reduction of NY with BNAH.Further,the reductions of alloxantin (AT) and HDT with BNAH were performed to give D and HID,respectively.The reduction of lipoic acid (LA) and viologens (V2+) with BNAH, which could not be reduced without A or NY, proceeded smoothly in their presence,and they proved to be useful as mediators for catalytic reduction of LA and V2+.