627-82-7Relevant articles and documents
Identification of Cyclic Acetals in Polyols by Mass Spectrometry
Sanders, Robert A.
, p. 1194 - 1197 (1983)
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Facile route to multigram synthesis of environmentally friendly non-isocyanate polyurethanes
Tryznowski, Mariusz,?widerska, Aleksandra,Zo?ek-Tryznowska, Zuzanna,Go?ofit, Tomasz,Parzuchowski, Pawe? G.
, p. 228 - 236 (2015)
Non-isocyanate poly(hydroxyurethanes) (NIPUs) are a fast growing class of polymers prepared by an environmentally friendly method without the use of toxic phosgene and isocyanates. In this work, we report a one-step procedure to synthesize bis(2,3-dihydroxypropyl)ether dicarbonate from a commercially available diglycerol. The product was characterized by 1H NMR, 13C NMR, and FTIR spectroscopies and for the first time by X-Ray diffraction measurements. Enantiomers RR and SS of the obtained monomer were observed in the single crystal structure. The bis(cyclic carbonate) monomer was used as a precursor for the synthesis of various NIPUs. The NIPUs were prepared in a non-solvent process. Spectral, thermal and rheological properties of the NIPUs formed from ten various diamines were compared.
Oligo-glycerol based non-ionic amphiphilic nanocarriers for lipase mediated controlled drug release
Aarti,Achazi, Katharina,Haag, Rainer,Mittal, Ayushi,Nie, Chuanxiong,Parmanand,Sharma, Sunil K.,Singh, Abhishek K.
, p. 37555 - 37563 (2020/10/28)
A new class of non-ionic amphiphiles is synthesized using a diaryl derivative of diglycerol as a central core and functionalizing it with long alkyl chains (C-12/C-15) and monomethoxy PEG moiety (Mn: 350/550) by following a chemo-enzymatic approach. The aggregation behavior of the amphiphiles in aqueous medium is studied by using dynamic light scattering (DLS) and fluorescence spectroscopy, whereas the size and morphology of the aggregates are studied by transmission electron microscopy (TEM). A hydrophobic dye, Nile red and a hydrophobic drug, nimodipine, are used to demonstrate the nano-carrier capability of these non-ionic amphiphilic systems and the results are compared with amphiphilic analogues obtained from the triaryl derivatives of triglycerol. Thein vitrocontrolled release of the encapsulated dye is successfully carried out in the presence of immobilizedCandida antarcticalipase (Novozym 435). Furthermore, cytotoxicity data is also collected which suggests that the amphiphiles are suitable for biomedical applications.
Catalytic behaviour of mesoporous metal phosphates in the gas-phase glycerol transformation
Lopez-Pedrajas,Estevez,Navarro,Luna,Bautista
, p. 92 - 101 (2016/06/09)
The catalytic behaviour of mesoporous simple (M = Al, Fe, Co, Mn) and binary (Al/M; M = Fe,V,Ca; molar ratio Al/Fe = 50; Al/V = 2; Al/Ca = 1) metal phosphates, synthesized by an economical gelation method, in the gas-phase glycerol reaction at temperatures between 220 °C and 280 °C, has been investigated. The morphology, textural properties and the acidity by pyridine TPD, of the phosphates were also determined. The activity of the phosphates in the formation of the main reaction product (acrolein) depended not only on their acidity (mainly acid sites of weak-medium strength) but also on the redox sites and morphology exhibited. Thus, the aluminium-vanadium phosphate showed the highest value of yield to acrolein, 62% (equivalent to a productivity of 0.88 gACRgcath) at 280 °C, whereas the amorphous FePO4 and AlPO4 were appreciably more active than the rest of the simple phosphates, exhibiting a high crystalline character. The apparent activation energy values obtained for the acrolein formation ranged between 18 and 91 kJ/mol. Based on the identified products in this study, some possible reactions involved in the glycerol transformation have been suggested.
