1120-24-7 Usage
Description
N,N-Dimethyldecylamine, also known as N,N-Dimethyl-1-decylamine, is a tertiary amine that serves as a valuable synthetic intermediate in the chemical industry. It is a liquid compound prepared by reacting N,N-dimethyldodecylamine, t-butyl hydroperoxide, vanadium oxyacetylacetonate, and t-butyl alcohol. Its unique chemical structure allows it to be used in various applications, including the synthesis of potential anticancer agents and biocides.
Uses
Used in Pharmaceutical Industry:
N,N-Dimethyldecylamine is used as a synthetic intermediate for the preparation of emodin (E523000) quaternary ammonium salt derivatives, which are potential anticancer agents. These derivatives have shown promise in targeting cancer cells and inhibiting their growth, making them a valuable addition to the arsenal of cancer-fighting drugs.
Used in Chemical Synthesis:
N,N-Dimethyldecylamine is used as a reactant in the synthesis of Benzyldecyldimethylammonium chloride (B234550), a biocide with applications in various industries. This biocide can be employed to control the growth of harmful microorganisms, such as bacteria and fungi, in different settings, including water treatment and industrial processes.
Used in Material Science:
N,N-Dimethyldecylamine (DMDA) is utilized in the study and development of advanced materials, such as pore expansion of aminopropyl-functionalized ethane-bridged bifunctional periodic mesoporous organosilicas (APEPMOs). This application allows for the creation of materials with enhanced properties, such as increased surface area and improved adsorption capabilities, which can be beneficial in various industrial applications.
Used in Chromatography:
N,N-Dimethyldecylamine is used in the preparation of a stationary phase (named QA C10) that has a quaternary ammonium embedded between a propyl and a decyl chain. This stationary phase is employed in chromatography techniques, which are crucial for the separation and analysis of complex mixtures in various fields, including pharmaceuticals, environmental science, and food technology.
Used in Nanotechnology:
N,N-Dimethyldecylamine is also used in the pore expansion of monodisperse phenylene-bridged organosilica spheres. These spheres have potential applications in catalysis, drug delivery, and sensing, thanks to their unique structural properties and the ability to control their size and shape through the use of N,N-Dimethyldecylamine in their synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 1120-24-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,2 and 0 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1120-24:
(6*1)+(5*1)+(4*2)+(3*0)+(2*2)+(1*4)=27
27 % 10 = 7
So 1120-24-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H27N/c1-4-5-6-7-8-9-10-11-12-13(2)3/h4-12H2,1-3H3
1120-24-7Relevant articles and documents
Overriding Intrinsic Reactivity in Aliphatic C?H Oxidation: Preferential C3/C4 Oxidation of Aliphatic Ammonium Substrates
Heilmann, Michael,Knezevic, Melina,Piccini, Giovanni Maria,Tiefenbacher, Konrad
, p. 12387 - 12391 (2020)
The site-selective C?H oxidation of unactivated positions in aliphatic ammonium chains poses a tremendous synthetic challenge, for which a solution has not yet been found. Here, we report the preferential oxidation of the strongly deactivated C3/C4 positions of aliphatic ammonium substrates by employing a novel supramolecular catalyst. This chimeric catalyst was synthesized by linking the well-explored catalytic moiety Fe(pdp) to an alkyl ammonium binding molecular tweezer. The results highlight the vast potential of overriding the intrinsic reactivity in chemical reactions by guiding catalysis using supramolecular host structures that enable a precise orientation of the substrates.
Deoxygenative hydroboration of primary, secondary, and tertiary amides: Catalyst-free synthesis of various substituted amines
An, Duk Keun,Jaladi, Ashok Kumar,Kim, Hyun Tae,Yi, Jaeeun
, (2021/11/17)
Transformation of relatively less reactive functional groups under catalyst-free conditions is an interesting aspect and requires a typical protocol. Herein, we report the synthesis of various primary, secondary, and tertiary amines through hydroboration of amides using pinacolborane under catalyst-free and solvent-free conditions. The deoxygenative hydroboration of primary and secondary amides proceeded with excellent conversions. The comparatively less reactive tertiary amides were also converted to the corresponding N,N-diamines in moderate yields under catalyst-free conditions, although alcohols were obtained as a minor product.
Dimethylamination of Primary Alcohols Using a Homogeneous Iridium Catalyst: A Synthetic Method for N, N-Dimethylamine Derivatives
Jeong, Jaeyoung,Fujita, Ken-Ichi
, p. 4053 - 4060 (2021/03/09)
A new catalytic system for N,N-dimethylamination of primary alcohols using aqueous dimethylamine in the absence of additional organic solvents has been developed. The reaction proceeds via borrowing hydrogen processes, which are atom-efficient and environmentally benign. An iridium catalyst bearing an N-heterocyclic carbene (NHC) ligand exhibited high performance, without showing any deactivation under aqueous conditions. In addition, valuable N,N-dimethylamine derivatives, including biologically active and pharmaceutical molecules, were synthesized. The practical application of this methodology was demonstrated by a gram-scale reaction.