79754-48-6

Upstream product

• 79754-55-5 4,5-bis-p-methoxyphenylpenta-2,4-dienoic acid 
• 79754-51-1 4,5-bis-p-methoxyphenyl-5-oxopentanoic acid 
• 70738-51-1 4,5-bis-(p-methoxyphenyl)pentanal 
• 6443-74-9 p-methoxy-α-p-methoxyphenylcinnamonitrile 
• 67295-37-8 3,4-bis-p-methoxyphenylbutanoic acid 
• 79754-50-0 ethyl 2-ethoxycarbonyl-4,5-bis-p-methoxyphenyl-5-oxopentanoate 
• 104-47-2 p-methoxybenzylnitrile 
• 67295-44-7 3,4-Bis-(4-methoxy-phenyl)-butyryl chloride 
• 79754-53-3 p-methoxy-α-p-methoxyphenylcinnamaldehyde 
• 123-11-5 4-methoxy-benzaldehyde 
• 79754-49-7 3-hydroxy-3,4-bis-(4-methoxy-phenyl)-butyric acid ethyl ester 
• 20498-71-9 1,2-bis(4-methoxyphenyl)ethan-1-ol 
• 67295-38-9 1, 2-bis(4-methoxyphenyl)prop-2-en-1-one 
• 70738-49-7 1,1-ethylenedioxy-4-hydroxy-4,5-bis-(p-methoxyphenyl)pentane 

Downstream Products

• 79754-54-4 7-hydroxy-4-p-hydroxybenzyl-1,2,3,4-tetrahydro-1-naphthol 
• 79754-58-8 7-hydroxy-4-p-hydroxybenzyl-3,4-dihydronaphthalen-1(2H)-one 
• 79813-33-5 (+/-)-sequirin D 
• 79754-57-7 7-methoxy-4-p-methoxybenzyl-1,2,3,4-tetrahydro-1-naphthol 
• 79813-32-4 (+/-)-di-O-methylsequirin D 
• 79754-56-6 7-methoxy-4-p-methoxybenzyl-3,4-dihydronaphthalen-1(2H)-one 

Relevant academic research and scientific papers

Naphthalene derivatives: A new series of selective cyclooxygenase-2 inhibitors

A new series of potent and selective cyclooxygenase-2 inhibitors have been prepared. Some of these compounds show good oral anti-inflammatory activity in rats.

Synthesis, Conformation, and Chirality of Di-O-methylsequirin D, a Biogenetically Novel Metabolite of Sequoia sempervirens

The synthesis of (+/-)-di-O-methylsequirin D (14; R=H) is reported.A Grignard reaction between 3,3-ethylenedioxypropylmagnesium bromide and deoxyanisoin gave the key alcohol (5), which was transformed into (14) by way of the acid (11) and tetralone (12).M

Synthesis of 5-p-Hydroxybenzyl-5,6-dihydro-2-naphthol, (+/-)-Sequirin D

A high-yield six-step synthesis of sequirin D (1a), a naturally occurring norlignan, is described.Michael addition of deoxyanisoin (2) to acrylonitrile gives a ketonitrile (3), which on Wolff-Kishner reduction is reduced and hydrolysed in situ to 4,5-bis-