88-98-2

Usage

Uses

Used in Plasticizer Industry:
Cyclohex-4-ene-1,2-dicarboxylic acid is used as a plasticizer for improving the flexibility and workability of various polymers and resins. It enhances the performance of materials by reducing their brittleness and increasing their durability.
Used in Construction Industry:
Cyclohex-4-ene-1,2-dicarboxylic acid is used in the preparation method of concrete coating. It helps in improving the adhesion, water resistance, and durability of the coating, providing a protective layer to the concrete surface.
Used in Printing Ink Industry:
Cyclohex-4-ene-1,2-dicarboxylic acid is used in the preparation method of polyester resin for two-piece can ink. It contributes to the ink's adhesion, gloss, and resistance to chemicals, ensuring high-quality printing on various surfaces.

InChI:InChI=1/C8H10O4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H2,(H,9,10)(H,11,12)

Upstream product

• 108-31-6 maleic anhydride 
• 106-99-0 buta-1,3-diene 
• 623-91-6 diethyl Fumarate 
• 107-11-9 1-amino-2-propene 
• 935-79-5 cis-1,2,3,6-tetrahydrophthalic anhydride 
• 77-79-2 3-Sulfolene 
• 110-17-8 (2E)-but-2-enedioic acid 
• 4841-84-3 dimethyl cis-1,2,3,6-tetrahydrophthalate 
• 4841-85-4 cis-4-cyclohexene-1,2-dicarboxylic acid diethyl diester 
• 17673-68-6 dimethyl trans-cyclohex-4-ene-1,2-dicarboxylate 
• 627-63-4 fumaryl dichloride 
• 6915-18-0 2-butenedioic acid 

Downstream Products

• 2453-43-2 4-Keto-5-nitrato-1,2-cyclohexandicarbonsaeure 
• 13287-81-5 4,5-bis(hydroxymethyl)-1-cyclohexene 
• 2403-25-0 4,5-dihydroxycyclohexane-1,2-dicarboxylic acid 
• 21544-03-6 glycidyl tetrahydrophthalate 
• 55063-90-6 5,8,11-trioxa-4,12-dioxo-2,3,13,14-di(4-cyclohexen-1,2-ylene)pentadecanedioic acid 
• 610-09-3 (1R,2S)-cyclohexane-1,2-dicarboxylic acid 
• 1687-30-5 cyclohexane-1,2-dicarboxylic acid 
• 46022-05-3 (1R,2R)-(-)-trans-cyclohexane-1,2-dicarboxylic acid 
• 88-99-3 benzene-1,2-dicarboxylic acid 
• 65-85-0 benzoic acid 
• 77210-71-0 (+)-(1S,6R)-8-cis-oxabicyclo[4.3.0]non-3-en-7-one 
• 85-43-8 1,2,3,6-Tetrahydrophthalic anhydride 
• 28907-18-8 4-cyclohexene-1,2-dicarboxamide 
• 1703-58-8 racem.-butane-1,2,3,4-tetracarboxylic acid 

Relevant academic research and scientific papers

RECYCLABLE POLYMERS BASED ON RING-FUSED GAMMA-BUTYROLACTONES

The invention discloses a class of new polymers, trans-ring-fused poly(4-hydroxybutyrate)s (RF-P4HB) that exhibit a unique set of properties, including robust thermal stability and mechanical strength, quantitative recyclability to the building block monomers via thermolysis and/or chemical catalysis, and convenient production from the chemical ring-opening polymerization under ambient temperature and pressure. Another unique property is the formation of crystalline stereocomplexed polymers with high melting temperature upon mixing the two enantiomeric RF-P4HB chains via stereocomplexing co-crystallization. This invention also provides the corresponding ring-fused lactone monomer structures that enable the synthesis of the RF-P4HB polymers, through trans-fusing of rings to the parent γ-butyrolactone ring. Furthermore, a polymerization or copolymerization process for the synthesis of RF-P4HB polymers and copolymers is disclosed.

A PROCESS FOR PREPARATION OF TRANS (LR,2R)-CYCLO HEXANE 1, 2-DICARBOXYLIC ACID

A commercially viable process for industrial preparation of trans-(l R,2R)-cyclohexane 1,2- dicarboxylic acid represented by compound of Formula-I, wherein the compound has more than 99% HPLC purity. The compound of Formula-I is a key intermediate in preparation of Lurasidone hydrochloride which is a well known antipsychotic agent used for treatment of schizophrenia.

PROCESS FOR PREPARING BENZISOTHIAZOL-3-YL-PEPERAZIN-L-YL-METHYL-CYCLO HEXYL-METHANISOINDOL-1,3-DIONE AND ITS INTERMEDIATES

The present invention discloses process for preparing benzisothiazol-3-yl- piperazin-l-yl-methyl-cyclo hexyl-methanisoindol-l,3-dione and intermediates thereof.

A METHOD FOR MAKING N-2,3-DIBROMOPROPYL-4-5-DIBROMOHEXAHYDROPHTHALIMIDE

The present invention relates to process technology suitable for producing, on a commercial scale, N-2,3-dibromopropyl-4,5-dibromohexahydrophthalimide.

Preparations and Crystal Structures of the 2-Oxides of Some Octahydro-3,2,1-benzoxathiazines and Octahydro-2H-3,1,2-benzoxazaphosphorines

The cis- and trans-fused 1-benzyl-1,4,4a,5,6,7,8,8a-octahydro-3,2,1-benzoxathiazine 2-oxides and cis- and trans-fused 1-benzyl-2-phenyl-1,4,4a,5,6,7,8,8a-octahydro-2H-3,1,2-benzoxazaphosphorine 2-oxides have been prepared from the cis- and trans-2-benzylaminocyclohexanemethanols and their structures have been determined by n.m.r. and crystallographic methods.

STEREOCHEMICAL STUDIES 83. SATURATED HETEROCYCLES 76. PREPARATION AND CONFORMATIONAL STUDY OF PARTIALLY SATURATED 3,1-BENZOXAZINES, 3,1-BENZOXAZIN-2-ONES AND 3,1-BENZOXAZINE-2-THIONES

The cis- and trans-2-amino-4-cyclohexene-1-carboxylic acids 1 and 3 react with imidates to give the condensed-skeleton, bicyclic cis- and trans-pyrimidin-4-ones 8 and 9.The amino acids 1 and 3 were reduced to the cis- and trans-1,3-aminoalcohols 6 and 7, which were cyclized by means of imidates to the bicyclic tetrahydro-4H-3,1-benzoxazines 10 and 11, or were converted, via the corresponding carbamates 14 and 15 into the tetrahydro-4H-3,1-benzoxazin-2(1H)-ones 16 and 17.The 2-thioxo analogues 18 and 19 were prepared by cyclization of the dithiocarbamates obtained from the aminoalcohols 6 and 7 by treatment with carbon disulphide.The trans-aminoalcohol 7 and its saturated analogue reacted with p-chlorobenzaldehyde to furnish the hexahydro 13 and octahydro-4H-3,1-benzoxazine 13a, respectively. 1H and 13C NMR studies showed that, similarly to the earlier-investigated analogues containing oxygen or unsubstituted nitrogen at position 1, the synthesized cis isomers 8, 10, 16 and 18 occurred as the preferred conformer in the heterocyclic twist inverse form of N-inside type (quasiaxal C6-N bond) (B).In the trans isomers containing a saturated C-2 atom (13 and 13a), H-2 and H-6 are in cis relative positions.

CARBOXY AND SUBSTITUTED CARBOXY ALKANOYL AND CYCLOALKANOYL PEPTIDES

Peptides of the formula STR1 wherein X is various amino or imino acids or esters are useful as hypotensive agents.