Enantioselective amination of silylketene acetals with [N-(arylsufonyl)imino]phenyliodinanes catalyzed by chiral dirhodium(II)  carboxylatesa

June 20, 2024

• Title:       

  Enantioselective amination of silylketene acetals with [N-(arylsufonyl)imino]phenyliodinanes catalyzed by chiral dirhodium(II)  carboxylates^a

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  Enantioselective amination of silylketene acetals with (N-arylsulfonylimino)phenyliodinanes catalyzed by chiral dirhodium(II) carboxylates: asymmetric synthesis of phenylglycine derivatives

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  Table 1

• Associated context:

  The reaction in CH2Cl2 proceeded smoothly at 0 ℃ to completion in less than 15 min, giving N-(2-nitrophenylsulfonyl)phenylglycine methyl ester (4b)21 in 95% yield after column chromatography on silica gel (Table 1, entry 1).