N, N′-bis(dichloro-s-triazinyl)-m-phe- nylenediamine 11 underwent macrocyclizative coupling reactions

July 05, 2024

• Title:       

  N, N′-bis(dichloro-s-triazinyl)-m-phe-  nylenediamine 11 underwent macrocyclizative coupling reactions

• Image Source:

  A general and high yielding fragment coupling synthesis of heteroatom-bridged calixarenes and the unprecedented examples of calixarene cavity fine-tuned by bridging heteroatoms

• Mark:

  Scheme 2

• Associated context:

  Being a reactive intermediate, N, N′-bis(dichloro-s-triazinyl)-m-phe-  nylenediamine 11 underwent macrocyclizative coupling reactions with 3-aminophenol 4 and m-phenylenediamines 5 and 6  to produce the desired hetereoatom-bridged calix[2]arene[2]-triazines 12, 13,20 and 14 in 46-58% yields (Scheme 2).